首页 > NSJ Bio > NSJ Bio/Cytokeratin 6 Antibody [clone KRT6A/2368] (V3850)/100 ug/V3850-100UG

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NSJ Bio/Cytokeratin 6 Antibody [clone KRT6A/2368] (V3850)/100 ug/V3850-100UG

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V3850-100UG

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NSJ Bio

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DescriptionThis mAb recognizes a protein of 56kDa, identified as Cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.Application NotesOptimal dilution of the Cytokeratin 6 antibody should be determined by the researcher.ImmunogenRecombinant human KRT6A protein was used as the immunogen for the Cytokeratin 6 antibody.StorageStore the Cytokeratin 6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all Cytokeratin 6 antibodies2. View all human protein microarray validated antibodies

NSJ Bioreagents已有20多年的历史。 NSJ Bio提供领先的、广泛使用的单克隆抗体以及单克隆和多克隆抗体的所有领域的研究，包括肿瘤，肿瘤生物标志物，细胞凋亡，免疫学，细胞生物学和转录因子。产品提供多种规格，以更好地适应研究人员的测试需求和预算限制。

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