DescriptionThe PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.Application NotesThe concentration stated for each application is a general starting point.Variations in protocols, secondaries and substrates may require the PAX5 antibody to be titered up or down for optimal performance.ImmunogenFull length human recombinant protein was used as the immunogen for this PAX5 antibody.StorageStore the PAX5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide). Related Products1. View all PAX5 antibodies2. View all human protein microarray validated antibodies

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