首页 > NSJ Bio > NSJ Bio/Recombinant p63 Antibody / Rabbit Monoclonal [clone TP63/1423R] (V3815)/100 ug/V3815SAF-100UG

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NSJ Bio/Recombinant p63 Antibody / Rabbit Monoclonal [clone TP63/1423R] (V3815)/100 ug/V3815SAF-100UG

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V3815SAF-100UG

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NSJ Bio

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Descriptionp63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts. Application NotesOptimal dilution of the recombinant p63 antibody should be determined by the researcher.ImmunogenFull-length human recombinant protein was used as the immunogen for the recombinant p63 antibody.StorageStore the recombinant p63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all p63 antibodies2. View all recombinant antibodies

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