首页 > NSJ Bio > NSJ Bio/SPTA1 Antibody / Spectrin alpha 1 [clone SPTA1/1810] (V3883)/100 ug/V3883-100UG

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NSJ Bio/SPTA1 Antibody / Spectrin alpha 1 [clone SPTA1/1810] (V3883)/100 ug/V3883-100UG

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V3883-100UG

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NSJ Bio

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DescriptionSpectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.Application NotesOptimal dilution of the SPTA1 antibody should be determined by the researcher.ImmunogenA portion of amino acids 356-475 from the human protein was used as the immunogen for the SPTA1 antibody.StorageStore the SPTA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all SPTA1 antibodies2. View all human protein microarray validated antibodies

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