DescriptionChloride intracellular channel protein 1 (CLIC1) is a part of the CLIC family of proteins. This family of proteins reconstitute in phospholipid vesicles and have been shown to have chloride channel action. CLIC1 may rotate between membrane-bound and soluble forms since it has been seen as a membrane protein and in the cytoplasm. When there is a lack of detergent, CLIC1 becomes membrane-bound and can act as an anion-selective channel. Recently, it has been shown that CLIC1 is required in angiogenesis and has a part in controlling integrin cell surface expression. Experimental results indicate that CLIC1 overexpression is a potential prognostic marker for gastric cancer, and demonstrated that CLIC1 expression is strongly correlated with lymph node metastasis, lymphatic invasion, perinueral invasion and pathological staging.Application NotesOptimal dilution of the CLIC1 antibody should be determined by the researcher.ImmunogenA full length recombinant human protein was used as the immunogen for the CLIC1 antibody.StorageStore the CLIC1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all CLIC1 antibodies2. View all human protein microarray validated antibodies

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