DescriptionChlorideintracellularchannelprotein1(CLIC1)isapartoftheCLICfamilyofproteins.Thisfamilyofproteinsreconstituteinphospholipidvesiclesandhavebeenshowntohavechloridechannelaction.CLIC1mayrotatebetweenmembrane-boundandsolubleformssinceithasbeenseenasamembraneproteinandinthecytoplasm.Whenthereisalackofdetergent,CLIC1becomesmembrane-boundandcanactasananion-selectivechannel.Recently,ithasbeenshownthatCLIC1isrequiredinangiogenesisandhasapartincontrollingintegrincellsurfaceexpression.ExperimentalresultsindicatethatCLIC1overexpressionisapotentialprognosticMarkerforgastriccancer,anddemonstratedthatCLIC1expressionisstronglycorrelatedwithlymphnodemetastasis,lymphaticinvasion,perinueralinvasionandpathologicalstaging.ApplicationNotesOptimaldilutionoftheCLIC1antibodyshouldbedeterminedbytheresearcher.ImmunogenAfulllengthrecombinanthumanproteinwasusedastheimmunogenfortheCLIC1antibody.StorageStoretheCLIC1antibodyat2-8oC(withazide)oraliquotandstoreat-20oCorcolder(withoutazide).RelatedProducts1.ViewallCLIC1antibodies2.Viewallhumanproteinmicroarrayvalidatedantibodies

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