首页 > NSJ Bio > NSJ Bio/CASR Antibody / Calcium Sensing Receptor [clone 11E9.] (RQ4484)/100 ug/RQ4484

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NSJ Bio/CASR Antibody / Calcium Sensing Receptor [clone 11E9.] (RQ4484)/100 ug/RQ4484

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RQ4484

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DescriptionThe calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.Application NotesOptimal dilution of the CASR antibody should be determined by the researcher.ImmunogenHuman CASR recombinant protein (amino acids Q926-S1078) was used as the immunogen for the CASR antibody.StorageAfter reconstitution, the CASR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. Related Products1. View all CASR antibodies

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