首页 > NSJ Bio > NSJ Bio/Drebrin Antibody / Debrin 1 [clone DBN1/2880] (V7711)/20 ug/V7711-20UG

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NSJ Bio/Drebrin Antibody / Debrin 1 [clone DBN1/2880] (V7711)/20 ug/V7711-20UG

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V7711-20UG

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NSJ Bio

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DescriptionDrebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2); and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.Application NotesOptimal dilution of the Drebrin 1 antibody should be determined by the researcher.ImmunogenA recombinant human partial protein (amino acids 150-281) was used as the immunogen for the Drebrin antibody.StorageStore the Drebrin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide). Related Products1. View all Drebrin 1 antibodies

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