首页 > NSJ Bio > NSJ Bio/HNRNPD Antibody / hnRNP D / AUF1 [clone 2B12] (RQ5858)/100 ug/RQ5858

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NSJ Bio/HNRNPD Antibody / hnRNP D / AUF1 [clone 2B12] (RQ5858)/100 ug/RQ5858

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RQ5858

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DescriptionHeterogeneous nuclear ribonucleoprotein D0 (HNRNPD) also known as AU-rich element RNA-binding protein 1 (AUF1) is a protein that in humans is encoded by the HNRNPD gene. It is mapped to 4q21.22. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.Application NotesOptimal dilution of the HNRNPD antibody should be determined by the researcher.ImmunogenRecombinant human protein (amino acids E88-N246) was used as the immunogen for the HNRNPD antibody.StorageAfter reconstitution, the HNRNPD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. Related Products1. View all HNRNPD antibodies

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