首页 > NSJ Bio > NSJ Bio/CD3e Antibody [clone UCHT1] (V3760)/100 ug/V3760SAF-100UG

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NSJ Bio/CD3e Antibody [clone UCHT1] (V3760)/100 ug/V3760SAF-100UG

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V3760SAF-100UG

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NSJ Bio

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DescriptionThis antibody recognizes the epsilon chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface.CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.Application NotesOptimal dilution of the CD3e antibody should be determined by the researcher.ImmunogenHuman infant thymocytes and peripheral blood lymphocytes from a Sezary Syndrome donor were used as the immunogen for the CD3e antibody.StorageStore the CD3e antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all CD3e antibodies

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