DescriptionFibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This mAb does not cross-react with MMP-2, MMP-9, or TIMP-2.Application NotesOptimal dilution of the Fibronectin antibody should be determined by the researcher.1.The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.ImmunogenHigh molecular weight proteins secreted by cultivated human fibroblasts were used as the immunogen for the Fibronectin antibody.The epitope of this mAb is located in the 29kDa N-terminal fibrin- and heparin-binding domain of fibronectin.StorageStore the Fibronectin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide). Citations (2)Related Products1. View all Fibronectin antibodies

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