首页 > NSJ Bio > NSJ Bio/ABCG2 Antibody (BCRP) (R30969)/100 ug/R30969

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NSJ Bio/ABCG2 Antibody (BCRP) (R30969)/100 ug/R30969

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DescriptionABCG2 (ATP-binding cassette, subfamily G, member 2) also known as ABCP, BCRP (Breast cancer resistance protein) or MRX (Mitoxantrone resistance-associated protein), is a protein that in humans is encoded by the ABCG2 gene. The gene encodes a membrane transporter belonging to the ATP-binding cassette (ABC) superfamily of membrane transporters, which are involved in the trafficking of biologic molecules across cell membranes.The protein is also a high capacity transporter for uric acid excretion in the kidney, liver, and gut.In vitro assays of isolated membrane preparations revealed a high-capacity, vanadate-sensitive ATPase activity associated with ABCG2 expression that was stimulated by compounds known to be transported by this protein.Application NotesTitration of the ABCG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.ImmunogenAmino acids 152-167 (KNHEKNERINTIIKEL-mouse) were used as the immunogen for this BCRP / ABCG2 antibody.StorageThe lyophilized ABCG2 antibody can be stored at 4oC to -20oC.After reconstitution, aliquot and store at -20oC.Avoid repeated freezing and thawing. Citations (1)Related Products1. View all ATP-Binding Cassette/ABC antibodies2. View all ABCG2 antibodies

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