首页 > NSJ Bio > NSJ Bio/AIM2 Antibody (R31802)/100 ug/R31802

提醒：代购产品，无质量问题不接受退换货，下单前请仔细核对信息。下单后请及时联系客服核对商品价格，订单生效后再付款。

NSJ Bio/AIM2 Antibody (R31802)/100 ug/R31802

价格：

登录查看

自营商城

解放采购

正品保障

及时交付

厂家直采

一站服务

货号：

R31802

品牌：

NSJ Bio

会员服务：

尊享会员价

贵宾专线

运费优惠

闪电退款

福利优惠

上门换新

友情提示

以上价格仅为参考，请联系客服询价。

免费咨询热线

4000-520-616

产品说明

DescriptionAbsent In Melanoma 2 is a protein that in humans is encoded by the AIM2 gene. AIM2 is a member of the Ifi202/IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. Though there has been virtually no biochemistry performed, a model based on cell-based or in vivo experiments has led to the current model of how AIM2 triggers the inflammasome. The C-terminal HIN domain binds double stranded DNA (either viral, bacterial, or even host) and acts as a cytosolic dsDNA sensor. This leads to the oligomerization of the inflammasome complex. The N-terminal pyrin domain of AIM2 interacts with the pyrin domain of another protein ASC (or Apoptosis-associated Speck-like protein containing a caspase activation and recruitment domain). ASC also contains a CARD domain (caspase activation and recruitment domain), that recruits procaspase-1 to the complex. This leads to the autoactivation of caspase-1, an enzyme that processes proinflammatory cytokines (IL-1b and IL-18).Application NotesOptimal dilution of the AIM2 antibody should be determined by the researcher.ImmunogenAmino acids 14-215 of human AIM2 were used as the immunogen for the AIM2 antibody.StorageAfter reconstitution, the AIM2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. Related Products1. View all AIM2 antibodies

NSJ Bioreagents已有20多年的历史。 NSJ Bio提供领先的、广泛使用的单克隆抗体以及单克隆和多克隆抗体的所有领域的研究，包括肿瘤，肿瘤生物标志物，细胞凋亡，免疫学，细胞生物学和转录因子。产品提供多种规格，以更好地适应研究人员的测试需求和预算限制。

链接：http://www.nsjbio.com/

温馨提示：不可用于临床治疗。

风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。