首页 > NSJ Bio > NSJ Bio/AKT2 Antibody (R31474)/100 ug/R31474

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NSJ Bio/AKT2 Antibody (R31474)/100 ug/R31474

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R31474

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DescriptionAKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. This gene is mapped to 19q13.2. AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1, -2 and -3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT2 seems also to be the principal isoform responsible of the regulation of glucose uptake. It is also specifically involved in skeletal muscle differentiation, one of its substrates in this process being ANKRD2. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers.Application NotesThe stated application concentrations are suggested starting amounts.Titration of the AKT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.ImmunogenAn amino acid sequence from the C-terminus of human AKT2 (DRYDSLGLLELDQRTHFPQFSYSASIRE) was used as the immunogen for this AKT2 antibody.StorageAfter reconstitution, the AKT2 antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing. Related Products1. View all AKT2 antibodies

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