首页 > NSJ Bio > NSJ Bio/CELA3B Antibody / Elastase 3B [clone CELA3B/1757] (V3449)/100 ug/V3449-100UG

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NSJ Bio/CELA3B Antibody / Elastase 3B [clone CELA3B/1757] (V3449)/100 ug/V3449-100UG

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V3449-100UG

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DescriptionThis mAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B), or Elastase 3B. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.Application NotesOptimal dilution of the CELA3B antibody should be determined by the researcher.ImmunogenA recombinant partial protein (aa 82-238) was used as the immunogen for the CELA3B antibody.StorageStore the CELA3B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all CELA3B antibodies

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