首页 > NSJ Bio > NSJ Bio/HLA-DR Antibody (MHC II) [clone 169-1B5.2] (V2584)/20 ug/V2584-20UG

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NSJ Bio/HLA-DR Antibody (MHC II) [clone 169-1B5.2] (V2584)/20 ug/V2584-20UG

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V2584-20UG

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NSJ Bio

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DescriptionThis antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.Application NotesOptimal dilution of the HLA-DR antibody should be determined by the researcher.ImmunogenHuman peripheral blood leukocytes were used as the immunogen for the HLA-DR antibody.StorageStore the HLA-DR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide). Related Products1. View all HLA-DR antibodies

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