首页 > NSJ Bio > NSJ Bio/Ki67 Antibody (R31458)/100 ug/R31458

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NSJ Bio/Ki67 Antibody (R31458)/100 ug/R31458

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R31458

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DescriptionProliferation-related Ki-67 antigen, also known as MKI67 or KIA, is a protein that in humans is encoded by the MKI67 gene. From study of a panel of human-rodent somatic cell hybrids, it has been demonstrated that a gene involved in the expression of the MKI67 antigen is located on chromosome 10. By in situ hybridization, Fonatsch et al. (1991) regionalized the MKI67 gene to chromosome 10q25-qter. By FISH, Traut et al. (1998) mapped the mouse Mki67 gene to chromosome 7F3-F5. KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis.Application NotesThe stated application concentrations are suggested starting amounts.Titration of the Ki67 antibody may be required due to differences in protocols and secondary/substrate sensitivity.ImmunogenHuman partial recombinant protein (AA 2860-3256) was used as the immunogen for this Ki67 antibody.StorageAfter reconstitution, the Ki67 antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing. Related Products1. View all Ki67 antibodies

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