首页 > NSJ Bio > NSJ Bio/PGE Receptor Antibody, EP1 subtype (R30660)/100 ug/R30660

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NSJ Bio/PGE Receptor Antibody, EP1 subtype (R30660)/100 ug/R30660

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R30660

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NSJ Bio

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DescriptionProstaglandin E Receptor 1 is a 402 amino acid protein with a predicted molecular mass of 44KD and has the seven transmembrane-spanning domains common to all G protein-coupled receptors. The PTGER1 gene is mapped to chromosome 19p13.1. The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E (PGE). Through a phosphatidylinositol-calcium second messenger system, Gq proteins mediate this receptor"s activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.Application NotesThe stated application concentrations are suggested starting amounts.Titration of the PGE Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.ImmunogenAn amino acid sequence from the C-terminus of human PGE Receptor EP1 subtype (AWEASSLRSSRHSGLSHF) was used as the immunogen for this PGE Receptor antibody.StorageAfter reconstitution, the PGE Receptor antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing. Related Products1. View all PGE Receptor antibodies

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