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NSJ Bio/Profilin-1 Antibody (R31726)/100 ug/R31726

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DescriptionProfilin-1 is a protein that in humans is encoded by the PFN1 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. At high concentrations, Profilin-1 prevents the polymerization of actin, whereas it enhances it at low concentrations. This gene is a 140-amino acid protein and major growth regulator of filamentous (F)-actin through its binding of monomeric (G)-actin. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.Application NotesThe stated application concentrations are suggested starting amounts.Titration of the Profilin-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.ImmunogenAn amino acid sequence from the C-terminus of human PFN1 (KEGVHGGLINKKCYEMASHLRRSQY) was used as the immunogen for this Profilin-1 antibody (100% homologous in human, mouse and rat).StorageAfter reconstitution, the Profilin-1 antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing. Related Products1. View all Profilin-1 antibodies

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