首页 > NSJ Bio > NSJ Bio/RELA Antibody NF-kB p65 (R31513)/100 ug/R31513

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NSJ Bio/RELA Antibody NF-kB p65 (R31513)/100 ug/R31513

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DescriptionTranscription factor p65, also known as NFKB3 or NF-kB p65, is a protein that in humans is encoded by the RELA gene. It is mapped to 11q13.1. RELA is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc, and it may play a role in inflammatory conditions of the peripheral nervous system. Phosphorylation and acetylation of RELA are crucial post-translational modifications required for NFkB activation. It has also been shown to modulate immune responses, and activation of the protein is positively associated with multiple types of cancer. In addition, RELA antagonizes TNFR1-JNK proliferative signals in epidermis and plays a nonredundant role in restraining epidermal growth.Application NotesThe stated application concentrations are suggested starting amounts.Titration of the RELA antibody may be required due to differences in protocols and secondary/substrate sensitivity.ImmunogenHuman partial recombinant protein (AA 99-551) was used as the immunogen for this RELA antibody.StorageAfter reconstitution, the RELA antibody can be stored for up to one month at4oC.For long-term, aliquot and store at -20oC.Avoid repeated freezing and thawing.Related Products1. View all NFkB p65 antibodies2. View all RELA antibodies

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