首页 > NSJ Bio > NSJ Bio/RIG-I Antibody / DDX58 (R32826)/100 ug/R32826

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NSJ Bio/RIG-I Antibody / DDX58 (R32826)/100 ug/R32826

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DescriptionRIG-I (retinoic acid-inducible gene I) is a RIG-I-like receptor dsRNA helicase enzyme that is encoded (in humans) by the DDX58 gene. RIG-I is part of the RIG-I-like receptor family, which also includes MDA5 and LGP2, and functions as a pattern recognition receptor that is a sensor for viruses such as influenza A, Sendai virus, and flavivirus. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.Application NotesOptimal dilution of the RIG-I antibody should be determined by the researcher.ImmunogenA recombinant human protein corresponding to amino acids H871-K925 was used as the immunogen for the RIG-I antibody.StorageAfter reconstitution, the RIG-I antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. Related Products1. View all RIG-I antibodies

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