More Information Product Details
Synonyms NIBR17 |
Product Type Chemical |
Properties
Formula C18H20N8O2 |
MW 380.4 |
CAS 944396-88-7 |
Purity Chemicals ≥95% |
Appearance Solid. |
Solubility Soluble in DMSO. |
Declaration Manufactured by SynKinase. |
Other Product Data Target: PI3K | Kinase Group: Lipid Kinase | Substrate: LipidClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet. |
InChi Key XZTYTIOLZIKUJR-UHFFFAOYSA-N |
Shipping and Handling
Shipping AMBIENT |
Short Term Storage +4°C |
Long Term Storage -20°C |
Use/Stability Stable for at least 2 years after receipt when stored at -20°C. |
Documents
MSDS Download PDF |
Product Specification Sheet
Datasheet Download PDF |
NIBR-17 is a pan class I PI3K inhibitor with IC(50) values of 1, 9.2, 9 and 20nM, respectively for PI3Kα - δ.Product References
Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors: M.T. Burger, et al.; ACS Med. Chem. Lett. 2, 34 (2010)