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MCA; 7-MeO-Coumarin-AcOH; 7-Methoxy-2-oxo-2H-1-benzopyran-4-acetic acid; NSC 378137

Chemical

C12H10O5

234.2

62935-72-2

Synthetic

≥97% (NMR)

White powder.

Soluble in DMF (50 mg/ml), acetone or DMSO.

Determined by NMR.

Manufactured by Chemodex.

Click here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet.

ZEKAXIFHLIITGV-UHFFFAOYSA-N

AMBIENT

+4°C

-20°C

Keep cool and dry.Protect from light and moisture.

Stable for at least 2 years after receipt when stored at -20°C.

No

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Florescent probe that is commonly used as a building block to synthesize coumarin-type fluorescent probes. Spectral data: λex 320 nm, λem 380 nm in methanol. It is used as a fluorescent label for peptides. It is widely used for developing FRET peptide substrates for analyzing protease activities and for HPLC derivatization by fluorescence detection.Product References(1) H. Mita, et al.; Anal. Biochem. 180, 131 (1989) | (2) C.G. Knight; Lett. Pept. Sci. 5, 1 (1998) | (3) C. Charitos, et al.; J. Pept. Res. 56, 373 (2000) | (4) G.A. Bannikov, et al.; J. Biol. Chem. 277, 16022 (2002) | (5) A. Ciencialova, et al.; J. Pept. Sci. 10, 470 (2004) | (6) L.E. Yandek, et al.; Biophys. J. 92, 2434 (2007) | (7) A. Lesner, et al.; Anal. Biochem. 375, 306 (2008)