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FabGennix/PDE1A Antibody/PD1A-101AP/

General Information

Product

PDE1A Antibody

Description

Affinity Purified Phosphodiesterase 1A Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence within amino acid region 1-50 on PDE1A protein. Common to all PDE1A variants.

SpecificityThis antibody will not label other PDE family members. This antibody will label all PDE1 variants including PDE1A1, PDE1A3, PDE1A5.

Accession #

NCBI: NP001009978.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q9JLL9

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.

Molecular Function

Hydrolase, calcium- and calmodulin-regulated 3,5-cyclic-GMP phosphodiesterase activity, metal ion binding

Subcellular LocationCytosol
ExpressionSeveral tissues, includingbrain, kidney, testes and heart.
StructureBelongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
Alternative Nomenclature

3 5 cyclic nucleotide phosphodiesteraseantibody61 kDa Cam PDEantibody

Calcium/calmodulin dependent 3 5 cyclic nucleotide phosphodiesterase 1AantibodyCalcium/calmodulin-dependent 3antibodyCalmodulin-dependent PhosphodiesteraseantibodyCam PDE 1Aantibody

HSPDE1AantibodyMGC26303antibodyPDE1Aantibody

Phosphodiesterase 1AantibodyPhosphodiesterase 1A calmodulin dependent antibody