General Information

Product

TLR10 Antibody

Description

Affinity Purified Toll-like receptor 10 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chimpanzee, Human, Monkey, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 380-430 on human TLR10 protein.

Accession #

GenBank: AAQ88667.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.67 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:20,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9BXR5

Overview

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Molecular Function

Receptor, transmembrane signaling receptor activity

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.

Structure

Binds MYD88 via their respective TIR domains (By similarity). Homodimer (Potential).

Alternative Nomenclature

CD 290 antibody

CD 290 antigen antibody

TLR10 antibody

Toll like receptor 10 antibody

UNQ315/PRO358 antibody