Description:
Osteoprotegerin(OPG) is identical to osteoclastogenesis inhibitory factor(OCIF), a soluble member of the tumor-necrosis factor receptor family that inhibits osteoclastogenesis. OPG is considered to play an important role in the regulation of bone resorption by modifying osteoclast differentiation. Osteoprotegerin is an independent risk factor for the progression of atherosclerosis and onset of cardiovascular disease. It can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity. OPG system may play a critical role in the development of osteolytic bone disease in multiple myeloma and that targeting this system may have therapeutic potential. OPG also plays a role in the vascular system.
Additional Information:
Name Mouse OPG ELISA Kit |
Related Product Names MGC29565|MGC93568|OCIF|OPG|Osteoclastogenesis inhibitory factor|Osteoprotegerin|TNFRSF 11B|TNFRSF11B|TR 1|TR1|TR11B_HUMAN|Tumor necrosis factor receptor superfamily member 11B |
Short Description Sandwich ELISA kit of Quantitative Detection for Mouse OPG |
Immunogen NSO, E22-L401 |
Standard Range 93.7pg/ml-6000pg/ml. Test has a sensitivity of |
Sample Type This kit is used for quantitative detection of mouse OPG in cell culture supernates, serum and plasma(EDTA). |
Specimen/Volumes Refer to Manual |
Swiss Prot Number O08712 |
Concentration Lot Specific |
Applications ELISA |
GI Number 18383 |
Stability Four months at 4C and eight months at -20C. |
Reactivity Reactive to Mouse. There is no detectable cross-reactivity with other relevant proteins. |
Kit Size 1x96 well plate |
Storage Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Intended Use Research Use Only |