Description:
Function: Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Additional Information:
Name | NATIVE HUMAN MMP-3 |
Related Product Names | STROMELYSIN-1 STMY1NATIVE HUMAN MMP-3MMP3 |
Gene Symbol | MMP3 |
Gene id | 4314 |
Alias Symbols | SL-1, STMY, STR1, CHDS6, MMP-3, STMY1, MGC126102, MGC126103, MGC126104, MMP3 |
Protein Name | Stromelysin-1 |
Description of Target | NATIVE HUMAN MMP-3 |
Swissprot ID | P08254 |
Protein Accession Num | NP_002413.1 |
Species Reactivity | Human |
Homology | Human |
Product Format | Purified Protein form human synovial fibroblasts - liquid |
Molecular Weight | Exhibits a doublet at 59/57 kDa which after activation with APMA reduces to a 50/38 kDa doublet that remains fairly stable. |
Swiss Prot Number | P08254 |
Purity | >98% |
Applications | E |
Clonality | Purified Protein |
Format | Purified Protein form human synovial fibroblasts - liquid |
Stability | 12 months from date of reconstitution. |
Reconstitution and Storage | Store at -20C only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. |
Reactivity | Human |
Storage | Store at -20oC only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. |
Lead Time | Domestic: within 2-3 weeks deliveryInternational: 2-3 weeks |
Intended Use | Research Use Only |
Additional Information | Buffer solution: TRIS buffered saline, pH 7.5Preservative: 0.05% - Sodium Azide (NaN3) |
:: | Instructions For Use: Enzyme is in the pro-enzyme form and therefore needs activating prior to use by the following method. Activation is achieved by the addition of 10% (v/v) of a 20 mM solution ofaminophenyl mercuric acetate in DMSO, followed by incubation at 37C for 8 hours. (If time is short substantial activation is achieved within 3 hours). |
