ACM-sf is a liquid medium prepared from primary human astrocyte cultures by using astrocyte medium (Cat #1801) without serum conditioned for 48 hours. The medium is sterile filtered and has a pH of 7.4 when equilibrated in an incubator with an atmosphere of 5% CO2/95% air.Astrocytes are the most abundant cells in the central nervous system (CNS). Astrocytes provide a variety of biological functions, such as supporting endothelial cells involved in blood-brain barrier formation, providing nutrients to neurons, maintaining extracellular ion balance, and promoting repair in the CNS. Astrocyte conditioned medium-serum free (ACM-sf) has been widely used to support the growth of neurons and endothelial cells in culture. ACM has also been shown to protect neurons from corticosterone-induced damage [1].ACM-sf is a liquid medium prepared from primary human astrocyte cultures by using astrocyte medium (Cat #1801) without serum conditioned for 48 hours. The medium is sterile filtered and has a pH of 7.4 when equilibrated in an incubator with an atmosphere of 5% CO2/95% air.
Specifications:
Catalog No. | 1811-sf |
Country of Manufacture | United States |
Product Code | ACM-sf |
Size/Quantity | 100 ml |
Product Use | ACM-sf is for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures. |
Storage | Store the medium at 4°C. Protect from light. |
Shipping Info | Gel ice. |
References | [1] Zhu Z, Yang R, Fu X, Wang Y, Wu G. (2006) \"Astrocyte-conditioned medium protecting hippocampal neurons in primary cultures against corticosterone-induced damages via PI3-K/Akt signal pathway.\" Brain Res 1114(1):1-10. |
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