This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.Keratinocyte Growth Factor-1 (KGF-1) is one of the 23 known members of the FGF family. All FGFs have two conserved cysteine residues and share 30 - 50% sequence identity at the amino acid level. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF-1 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGF receptor 2b. KGF-1 is important in kidney and lung development, angiogenesis, and wound healing.
Specifications:
Catalog No. | 104-07 |
Country of Manufacture | United States |
Product Code | rhKGF-1 |
Size/Quantity | 2 μg |
Product Use | This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
Storage | Store at -20°C after receiving. Upon Reconstitution, store at 2-8°C for up to one week. For maximal stability, aliquot and store at -20°C. Avoid repeated freeze/ thaw cycles. |
Shipping Info | Dry ice |
Synonyms | FGF-7, HBGF-7 |
AA Sequence | MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNF KELILENHY NTYASAKWT HNGGEMFVAL NQKGIPVRGK KTKKEQKTAH FLPMAIT |
Source | Escherichia coli |
Molecular Weight | Approximately 19.0 kDa, a single, non-glycosylated polypeptide chain containing 164 amino acids. |
Purity | >96% by SDS-PAGE and HPLC analyses. |
Biological Activity | Fully biologically active. The ED50 is |
Physical Appearance | White lyophilized powder. |
Formulation | Lyophilized from a 0.2μm filtered solution in 20mM PB, pH 8.0, 1M NaCl. |
Endotoxin | |
Reconstitution | Reconstitute in sterile distilled water containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. |
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