eEnzyme/Beta-2 Adrenergic Receptor (ADRB2) ACTOneTM Stable Cell /CL-01-ADRB2/1 Ea
| CL-01-ADRB2 | | Name | Beta-2 Adrenergic Receptor (ADRB2) ACTOneTM Stable Cell Line | | Description | This cell line is a HEK-293-CNG cell line that expresses a recombinant human ADRB1. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. The assay allows both end-point and kinetic measurement of intracellular cAMP changes with a FLIPR or a fluorescence microplate reader. | | Application | cAMP dependent human ADRB2 cell-based assay; Cell-based high-throughput screening of human ADRB2 agonists/antagonists. | | Size | 1x 106 cells | | Detection | FlexStation or microplate reader | |
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