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Hampton research/Index • Index HT/Index HT/1 ml, Deep Well block format/HR2-134

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HR2-134

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Applications FeaturesTube or Deep Well block format DescriptionIndex is designed as a 96 reagent crystallization screen that combines the strategies of the grid, sparse matrix, and incomplete factorial screening with traditional, contemporary, and new crystallization reagent systems into a highly effective and efficient format.Index, as the name implies, efficiently samples a series of specially formulated reagent zones to identify which reagent class or classes and pH are effective in producing crystals or limiting sample solubility. Results from Index can be used to design optimization experiments and to identify follow on screens by reagent class. For example, positive results with salt based reagents in Index may be followed up with further screening using SaltRx or Grid Screen Salt HT. Success with polymer based reagents in Index may be followed up with further screening using PEGRx or PEG/Ion.Index utilizes a broad, yet refined portfolio of crystallization reagent systems. These include the following: (1) traditional salts such as Ammonium sulfate and Sodium chloride versus pH; (2) neutralized organic acids such as Sodium malonate and Tacsimate; (3) High salt concentration mixed with low polymer concentration as well as high polymer concentration mixed with low salt concentration and; (4) Low ionic strength using polymers such as PEG, MPD, Pentaerythritols versus pH. These reagent systems are formulated across a sparse matrix and incomplete factorial of concentration ranges, sampling a pH range of 3 to 9.Index contains 96 unique reagents, 10 ml each.Index HT contains 96 unique reagents in a single Deep Well block format.Ready-to-use reagents are sterile filtered and formulated with ultra-pure Type 1 water, using the highest purity salts, polymers, organics and buffers. Individual reagents are available through the Hampton Research Custom Shop.Measured pH range of kit is 3 to 9 at 25°C Average measured pH of kit is 6.8 at 25°C Median measured pH of kit is 6.9 at 25°C Show More

美国Hampton Research公司是蛋白质晶体研究方面的专家，是一个从事蛋白质晶体研究研制的专业公司，为全球科研人员提供晶体研究工具和试剂，完整的晶体培养体系；同时提供晶体设计和合成方面的服务。其提供的试剂长期以来在该领域居于领先地位，为广大研究人员提供了极大的方便，促进了蛋白质晶体的研究，为世界范围内的蛋白质晶体研究人员所信赖。