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Hampton research/Silica Hydrogel Kit/Silica Hydrogel kit/500 µl, 24 tubes/HR2-310

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HR2-310

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Hampton research

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Applications Features DescriptionGels are a very efficient media for growing macromolecular crystals.1-5 Silica gels in particular have the advantage in that they are stable, usable over a wide range of temperatures (0-60°C), and are compatible with a wide variety of precipitants and additives used for crystal growth. The Silica Hydrogel Kit provides you with the materials you need to make gels at room temperature which polymerize rapidly and form a porous matrix with a pH of 7.0. The neutral pH allows one to use the gel with minimal influence on the pH of the precipitant.Why use the Silica Hydrogel for crystallization? Depending upon the macromolecule and selected conditions, gels can reduce nucleation and sedimentation, provide added stability, and allow crystals to grow larger. The porous network minimizes natural convection. Crystals are suspended in the gel network so that they do not form sediments and can grow free from strain exerted by the container or other crystals. The gel fissures around a growing crystal forming a cusp-like cavity. Heterogeneous and secondary nucleation are reduced in the presence of a silica hydrogel.3 The Silica Hydrogel can be used for liquid-gel, liquid-gel-liquid, vapor diffusion, as well as dialysis crystallization methodologies. The gel is compatible with a wide range of salts, polymers, organic solvents, and buffers used for macromolecular crystallization in a pH range from 3 to 10.Each Silica Hydrogel kit contains twelve 500 microliter tubes of sodium silicate solution and twelve 500 microliter tubes of acetic acid solution. All solutions are formulated using ultra-pure water and are sterile filtered. Crystallization accessories are sold separately. Show More

美国Hampton Research公司是蛋白质晶体研究方面的专家，是一个从事蛋白质晶体研究研制的专业公司，为全球科研人员提供晶体研究工具和试剂，完整的晶体培养体系；同时提供晶体设计和合成方面的服务。其提供的试剂长期以来在该领域居于领先地位，为广大研究人员提供了极大的方便，促进了蛋白质晶体的研究，为世界范围内的蛋白质晶体研究人员所信赖。