tech_banner
Fitzgerald/PON1 antibody/10R-5358/100 ul

OVERVIEW:

Synonyms Cross Reactivity Applications Immunogen
Monoclonal PON1 antibody, Anti-PON1 antibody, Paraoxonase 1 antibody, ESA antibody, PON antibody, PON1, PON 1, PON-1, PON 1 antibody, PON-1 antibody
Human, Monkey
FC, WB
PON1 antibody was raised in mouse using a full length recombinant protein of human PON1 (NP_000437) produced in HEK293T cells, as the immunogen.

SPECIFICATIONS:

Host Clone Isotype Method of Purification Form & Buffer Concentration
Mouse
2A9
IgG1
PON1 antibody was purified by affinity chromatography.
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
500 ug-1 mg/ml

STORAGE & SAFETY:

Storage
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations
FC: 1:100, WB: 1:500-2000

GENERAL INFORMATION:

Biological Significance
PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may mediate an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.