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Standard Neuron Device (150um microgroove barrier) Cat. No.: SND150 Price per

一包5个

现货 Size: ~ 22 mm - ~23mmThe 150 um neuron device with its shorter microgroove barrier is suitable for Researchers who would like to isolate both axons and dendrites. It is also suitable for certain neuronal cultures that do not grow long processes. Researchers who wish to study the early events of axonal and dendritic growth may also find the 150 um device useful. The 150 um device also offers the benefits of fluidic isolation and culture organization for transport studies.

The Neuron Device

Important: Please note that the Neuron Microfludic Device currently consists of the PDMS part only. Cover glass, cover dishes, related equipment, and other accessories are to be provided by the researcher. For indepth information about the neuron device and its use we recommend reading our detailed protocol which is available to our customers by request.

Click here to download our order form then email to: xonamicrofluidics@gmail.com or Fax Order Form to: 951-346-5566Nat Methods. 2005 Aug;2(8):599-605.A microfluidic culture platform for CNS axonal injury, regeneration and transport.Taylor AM, Blurton-Jones M, Rhee SW, Cribbs DH, Cotman CW, Jeon NL.The Neuron Device offered by Xona Microfluidics LLC is fabricated out of optically transparent and biologically inert Polydimethylsiloxane (PDMS). The Neuron Device consists of two chambers connected by microgrooves.The neuron device also makes it possible for the researcher to fluidically isolate cell bodies from axons. The device consists of two chambers connected by a much smaller microgroove barrier. The hydrostatic pressure between the two chambers separated by the microgrooves allows the researcher to fluidically isolate each chamber. This is accomplished by keeping the volumes in the wells on one side of the device higher than the other side of the device. The difference in volume creates hydrostatic pressure thus fluidically isolating each compartment.The total volume of the device is about 600 ul thus the researcher uses less of the expensive reagents typically used in neuronal culture.The neuron device also makes it possible to perform axotomy, cutting axons via vacuum aspiration in the distal chamber and observing their regrowth. enlarge image enlarge imageRequest Product InformationFor indepth information about the Neuron Device and its use we recommend reading our detailed protocol which is available to our customers by request. Please use thecontact form to request additional information or email us at:xonamicrofluidics@gmail.com