Matreya/N-(1-Adamantaneacetyl)-ceramide trihexoside/1947/1 mg-蚂蚁淘生物

Catalog #:1947

Scientific Name:N-(1-Adamantaneacetyl)-ceramide trihexoside

Common Name:N-Adamantyl-globotriaosylceramide; AdaGb₃

Empirical Formula:C₄₈H₈₃NO₁₈

SDSView Safety Data Sheet

Data Sheet:View Data Sheet

Formula Weight:962

Unit:1 mg

Source:semisynthetic

Purity:98+%

Analytical Methods:TLC; identity confirmed by MS

Natural Source:porcine

Solubility:chloroform/methanol, 2:1, methanol, DMF

Physical Appearance:solid

Storage:-20°C

Dry Ice:No

Hazardous:No

Literature References:1. C. Lingwood et al., Adamantyl Glycosphingolipids Provide a New Approach to the Selective Regulation of Cellular Glycosphingolipid Metabolism. The Journal of Biological Chemistry 286:24 (2011) 21413-214262. M. Mylvaganam and C. Lingwood, Adamantyl Globotriaosyl Ceramide: A Monovalent Soluble Mimic Which Inhibits Verotoxin Binding to Its Glycolipid Receptor. Biochemical and Biophysical Research Communications 257:2 (1999) 391-3943. J. Fantini et al., A novel soluble analog of the HIV-1 fusion cofactor, globotriaosylceramide (Gb3 ), eliminates the cholesterol requirement for high affinity gp120/Gb 3 interaction. Journal of Lipid Research 43 (2002) 1670-16794. C. Lingwood et al., Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog. Journal of Biological Chemistry 283 (2008) 4501-4511

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