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MCLAB/CHAPSO/DCSO101/1 Ea
CHAPSO(3-[(3-cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate) is a zwitterionic detergent used to solubilize proteins. Due to its low light absorbance in the ultraviolet region of the electromagnetic spectrum, CHAPSO is useful for researchers monitoring ongoing chemical reactions or protein-protein binding with UV/Vis spectroscopy

Description: CHAPSO(3-[(3-cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate) is a zwitterionic detergent used to solubilize proteins. Due to its low light absorbance in the ultraviolet region of the electromagnetic spectrum, CHAPSO is useful for researchers monitoring ongoing chemical reactions or protein-protein binding with UV/Vis spectroscopy. 

Applications:

  • Solublizies proteins in non-denaturing state
  • Helps monitor membrane proteins due to its low background absorbance in the UV region

Synonyms:3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonateMolecular Formula:C32H58N2O8SMelting point (Mp):184-186°CReference:

  • L.M. Hjelmeland, Proc. Natl. Acad. Sci. USA, 77, 6368 (1980)