错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。报价查询表错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。所有产品或产品名称开头为:A B C D E F G H I J K L M N O P Q R S T U V W X Y Z错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。错误您正在查看错误的购物车。 BAY1125976 is an orally bioavailable inhibitor of the serine/threonine protein kinase AKT (protein kinase B) isoforms 1 and 2 (AKT1/2) with potential antineoplastic activity. AKT1/2 inhibitor BAY1125976 selectively binds to and inhibits the phosphorylation and activity of AKT1/2 in a non-ATP competitive manner, which may result in the inhibition of the phosphatidylinositol 3 (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway. This may lead to both the reduction of cell proliferation and the induction of cell apoptosis in AKT-overexpressing tumor cells. The AKT signaling pathway is often deregulated in cancer and is associated with tumor cell proliferation, survival and migration.
MedKoo Cat#: 206151 Name: BAY1125976 CAS#: NONE Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis:
Synonym: BAY1125976; BAY 1125976; BAY-1125976.
IUPAC/Chemical Name: NONE
Technical Data
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Harmonized System Code: 293490
Additional Information
References