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Adipogen/Bikaverin/AG-CN2-0130-M001/1 mg
More Information Product Details Synonyms Product Type Properties Formula MW CAS RTECS Source/Host Chemicals Purity Chemicals Appearance Solubility Declaration InChi Key Shipping and Handling Shipping Short Term Storage Long Term Storage Handling Advice Use/Stability Documents MSDS Product Specification Sheet Datasheet
NSC 215139; BRN 0358013; Lycopersin; Mycogonin; Passiflorin
Chemical
C20H14O8
382.3
33390-21-5
DM2901000
Isolated from Fusarium sp.
≥95% (TLC)
Dark red solid.
Soluble in DMSO.
Manufactured by BioLinks K.K. with courtesy strain from The Kitasato Institute.
ZOQMSOSJEWBMHP-UHFFFAOYSA-N
AMBIENT
+4°C
-20°C
Keep cool and dry.
Stable for at least 3 years after receipt when stored at -20°C.
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  • Antibiotic [1].
  • Antiprotozoal [1].
  • Antifungal [2].
  • Anticancer [3-7].
  • ATP synthesis inhibitior [3, 4].
  • Haemolytic agent [5].
  • Antioomycete [8].
  • Spermidine-induced autoactivation inhibitor [9].
  • Plasma hyaluronan-binding protein (PHBP) inhibitor (active form) [9].
  • Review [10].
Product References
  • Bikaverin, an antibiotic from ibberella fujikoi, effective against Leishmania brasiliensis: J. Balan, et al.; Folia Microbiol. 15, 479 (1970)
  • Isolation and characterization of a fungal vacuolation factor (bikaverin): J.W. Cornforth, et al.; J. Chem. Soc. Perkin 16, 2786 (1971)
  • New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors: J. Fuska, et al.; Neoplasma 22, 335 (1975)
  • Effects of bikaverin on purine nucleotide synthesis and catabolism in Ehrlich ascites tumor cells in vitro: J.F. Henderson, et al.; Biochem. Pharmacol. 26, 1973 (1977)
  • Inhibition of mitochondrial functions by the antibiotics, bikaverin and duclauxine: L. Kovac, et al.; J. Antibiot. (Tokyo) 31, 616 (1978)
  • Effects of selected secondary metabolites of Fusarium moniliforme on unscheduled synthesis of DNA by rat primary hepatocytes: W.P. Norred, et al.; Food Chem. Toxicol. 30, 233 (1992)
  • Search for cell motility and angiogenesis inhibitors with potential anticancer activity: beauvericin and other constituents of two endophytic strains of Fusarium oxysporum: J. Zhan, et al.; J. Nat. Prod. 70, 227 (2007)
  • Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans: S.W. Son, et al.; J. Appl. Microbiol. 104, 692 (2008)
  • Purpurin as a specific inhibitor of spermidine-induced autoactivation of the protease plasma hyaluronan-binding protein: N. Nishimura, et al.; Biol. Pharm. Bull. 33, 1430 (2010)
  • Bikaverin production and applications: M.C. Limon, et al.; Appl. Microbiol. Biotechnol. 87, 21 (2010) (Review)