Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. Usp11 belongs to the ubiquitin-specific protease family. It helps in repairing DNA damage. It has been found to interact with RanBPM, a RanGTP-binding protein.UHX1

Additional Information

Product Name: Also Known As: Catalog No.: Size: Molecular Weight: Species: Source: Stock: Concentration: Quality Assurance: Storage: PDF Data Sheet: NCBI RefSeq: Image(s): Shipping Method: References:

GST-USP11

UHX1

H6110

25 µg

109.8 kDa

Human

Sf9 insect cells

20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol

See tube label

~85% by SDS-PAGE, see datasheet for gel image

Store at -80°C; avoid multiple freeze-thaw cycles

PDF Datasheet， MSDS

NM_004651

N/A

Dry ice shipping

1. Wanson DA, et al. (1996) Hum Mol Genet 5, 533 – 538.2. Ideguchi H, et al. (2002) Biochem J 367(Pt 1), 87 – 95.3. Reyes-Turcu FE, et al.(2009) Annu Rev Biochem 78, 363 – 397.

Details

Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. Usp11 belongs to the ubiquitin-specific protease family. It helps in repairing DNA damage. It has been found to interact with RanBPM, a RanGTP-binding protein.