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Items 1 to 401 of 401 totalNocodazole, Microtubule Inhibitor / CRISPR Editing Enhancer Nocodazole, Microtubule Inhibitor / CRISPR Editing EnhancerNocodazole, Microtubule Inhibitor / CRISPR Editing Enhancer$79.00Catalog No. M60331A potent microtubule inhibitor to inhibit mitosis and CRISPR editing enhancer.(+)-JQ1, BET Inhibitor(+)-JQ1, BET Inhibitor(+)-JQ1, BET Inhibitor$109.00$139.00Catalog No. M60139A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4(R)-2-HG， a-KG-dependent dioxygenases inhibitor (R)-2-HG， a-KG-dependent dioxygenases inhibitor(R)-2-HG， a-KG-dependent dioxygenases inhibitor$69.00Catalog No. M60104An a-KG-dependent dioxygenases inhibitor(S)-crizotinib, MTH1 Inhibitor(S)-crizotinib, MTH1 Inhibitor(S)-crizotinib, MTH1 Inhibitor$99.00Catalog No. M60208A novel potent, selective and cell permeable MTH1 inhibitor.(Z)-4-Hydroxytamoxifen, CRISPR Editing Enhancer(Z)-4-Hydroxytamoxifen, CRISPR Editing Enhancer(Z)-4-Hydroxytamoxifen, CRISPR Editing Enhancer$89.00Catalog No. M60324Previously characterized as an Estrogen Receptor antagonist and now found to improve genome-editing specificity in CRISPR-mediated gene editing1,4-DPCA, Prolyl 4-hydroxylase (P4H) Inhibitor1,4-DPCA, Prolyl 4-hydroxylase (P4H) Inhibitor1,4-DPCA, Prolyl 4-hydroxylase (P4H) Inhibitor$29.00Catalog No. M60288A selective and cell permeable prolyl 4-hydroxylase (P4H) inhibitor.1-methyl-D-tryptophan (D-1MT), IDO Inhibitor1-methyl-D-tryptophan (D-1MT), IDO Inhibitor1-methyl-D-tryptophan (D-1MT), IDO Inhibitor$29.00Catalog No. M60291A potent and selective indoleamine 2,3-dioxygenase (IDO) inhibitor.4SC-202, HDAC/LSD1 Dual Inhibitor 4SC-202, HDAC/LSD1 Dual Inhibitor4SC-202, HDAC/LSD1 Dual Inhibitor$109.00Catalog No. M60230A potent, selective and orally bioavailable HDAC/LSD1 dual Inhibitor.5-Azacytidine, DNA Methyltransferase Inhibitor5-Azacytidine, DNA Methyltransferase Inhibitor5-Azacytidine, DNA Methyltransferase Inhibitor$59.00Catalog No. M60131A classic DNA methyltransferase inhibitor, incorporates into DNA forming covalent adducts with cellular DNMT, depleting enzyme activity.A-366, G9a/GLP HMTase InhibitorA-366, G9a/GLP HMTase InhibitorA-366, G9a/GLP HMTase Inhibitor$139.00Catalog No. M60210A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.A01, Smurf1 E3 Ubiquitin Ligase InhibitorA01, Smurf1 E3 Ubiquitin Ligase InhibitorA01, Smurf1 E3 Ubiquitin Ligase Inhibitor$109.00Catalog No. M60249A potent and selective Smurf1 E3 ubiquitin ligase inhibitor.A769662, AMPK ActivatorA769662, AMPK ActivatorA769662, AMPK Activator$79.00Catalog No. M60020A potent allosteric AMPK activator.A83-01, TGF- Inhibitor A83-01, TGF- InhibitorA83-01, TGF- Inhibitor$59.00Catalog No. M60021A potent and selective TGF- pathway inhibitor (targeting ALK4, ALK5 and ALK7).AA92593, Antagonist of Melanopsin-mediated Photo-transductionAA92593, Antagonist of Melanopsin-mediated Photo-transductionAA92593, Antagonist of Melanopsin-mediated Photo-transduction$139.00Catalog No. M60143A potent and selective small molecule antagonist of melanopsin-mediated photo-transduction.Abiraterone, CYP17 inhibitor Abiraterone (CB-7598)Abiraterone, CYP17 inhibitor Abiraterone (CB-7598)Abiraterone, CYP17 inhibitor Abiraterone (CB-7598)$69.00Catalog No. M60031A first-in-class CYP17 inhibitor approved to treat castration-resistant prostate cancer.ABT-199, BCL-2 inhibitorABT-199, BCL-2 inhibitorABT-199, BCL-2 inhibitor$99.00Catalog No. M60075A potent BCL-2 selective (BCL-X L) inhibitor with clinical efficacy.ACY-1215 (Rocilinostat), HDAC6 inhibitorACY-1215 (Rocilinostat), HDAC6 inhibitorACY-1215 (Rocilinostat), HDAC6 inhibitor$109.00Catalog No. M60076A highly potent, selective, and orally bioavailable inhibitor of histone deacetylase 6 (HDAC6).ADC Toxin Monomethyl auristatin E (MMAE)ADC Toxin Monomethyl auristatin E (MMAE)ADC Toxin Monomethyl auristatin E (MMAE)InquiryCatalog No. T60001Antimitotic agent used as toxin linked to antibody.ADC Toxin Monomethyl auristatin F (MMAF)ADC Toxin Monomethyl auristatin F (MMAF)ADC Toxin Monomethyl auristatin F (MMAF)Inquiryxcessbio公司品牌 总代理Catalog No. T60002Antimitotic agent used as toxin linked to antibodyAdipoRon, Adiponectin Receptor/AdipoR agonist AdipoRon, Adiponectin Receptor/AdipoR agonistAdipoRon, Adiponectin Receptor/AdipoR agonist$129.00Catalog No. M60152A novel, highly potent, selective and orally active small molecule agonist of adiponectin receptor (AdipoR).AG-120 (Ivosidenib), IDH1 InhibitorAG-120 (Ivosidenib), IDH1 InhibitorAG-120 (Ivosidenib), IDH1 Inhibitor$129.00Catalog No. M60318A potent, selective and reversible inhibitor of IDH1 in clinical trials.AG-221 (Enasidenib), IHD2 InhibitorAG-221 (Enasidenib), IHD2 InhibitorAG-221 (Enasidenib), IHD2 Inhibitor$129.00Catalog No. M60296A potent and selective inhibitor of IDH2 R140Q mutant.AGI-5198 (IDH-C35), Mutant IDH1 Inhibitor AGI-5198 (IDH-C35), Mutant IDH1 InhibitorAGI-5198 (IDH-C35), Mutant IDH1 Inhibitor$109.00Catalog No. M60068The first highly potent and selective mutant IDH1 inhibitor that was shown to have anti-tumor efficacy in vivo.AGI-6780, Mutant IDH2 Inhibitor AGI-6780, Mutant IDH2 InhibitorAGI-6780, Mutant IDH2 Inhibitor$109.00Catalog No. M60105The first highly potent and selective small molecule mutant IDH2 inhibitor.AK-7, SIRT2 InhibitorAK-7, SIRT2 InhibitorAK-7, SIRT2 Inhibitor$69.00Catalog No. M60107A cell- and brain-permeable, selective sirtuin SIRT2 inhibitor, displays no effect on SIRT1 or SIRT3.AMI-1, Histone Methyltransferase InhibitorAMI-1, Histone Methyltransferase InhibitorAMI-1, Histone Methyltransferase Inhibitor$79.00Catalog No. M60272A potent and specific small molecule inhibitor of histone methyltransferase targeting yeast Hmt1p and human PRMT1.APY29, IRE1a Modulator APY29, IRE1a ModulatorAPY29, IRE1a Modulator$109.00Catalog No. M60168A highly potent and selective small molecule modulator of IRE1 .AR7, RAR antagonist AR7, RAR antagonistAR7, RAR antagonist$129.00Catalog No. M60116A highly potent and selective enhancer of the chaperone-mediated autophagy (CMA) through antagonizing RAR .AS2034178, GPR40 Agonist AS2034178, GPR40 AgonistAS2034178, GPR40 Agonist$139.00Catalog No. M60221A potent, selective and orally bioavailable GPR40 (FFA1) agonist.AS8351, KDM5B InhibitorAS8351, KDM5B InhibitorAS8351, KDM5B Inhibitor$109.00Catalog No. M60330A potent iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B).Atglistatin, Adipose Triglyceride Lipase (ATGL) Inhibitor Atglistatin, Adipose Triglyceride Lipase (ATGL) InhibitorAtglistatin, Adipose Triglyceride Lipase (ATGL) Inhibitor$119.00Catalog No. M60150A highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL).AZD2014, mTOR InhibitorAZD2014, mTOR InhibitorAZD2014, mTOR Inhibitor$169.00Catalog No. M60090A highly potent, selective and ATP-competitive mTOR inhibitor with a high level of selectivity against other members of the PIKK family.AZD6244 (Selumetinib), MEK Inhibitor AZD6244 (Selumetinib), MEK InhibitorAZD6244 (Selumetinib), MEK Inhibitor$109.00Catalog No. M60067A potent and highly selective non-ATP competitive MEK inhibitor in clinical trials.AZD8055, mTOR InhibitorAZD8055, mTOR InhibitorAZD8055, mTOR Inhibitor$69.00Catalog No. M60091A highly potent, selective and ATP-competitive mTOR inhibitor with 1,000-fold selectivity against all PI3K isoforms.Azidothymidine (AZT), Reverse Transcriptase Inhibitor Azidothymidine (AZT), Reverse Transcriptase InhibitorAzidothymidine (AZT), Reverse Transcriptase Inhibitor$29.00Catalog No. M60238A selective, orally bioavailable and brain penetrant| reverse transcriptase inhibitor.b-AP15 (NSC687852), Deubiquitinases Inhibitorb-AP15 (NSC687852), Deubiquitinases Inhibitorb-AP15 (NSC687852), Deubiquitinases Inhibitor$89.00Catalog No. M60251A potent and selective deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage.BAF312, S1P1/5 Selective AgonistBAF312, S1P1/5 Selective AgonistBAF312, S1P1/5 Selective Agonist$129.00Catalog No. M60039A potent and selective sphingosine 1-phosphate (S1P1/5) receptor agonist in clinical trials.BAM7, BAX ActivatorBAM7, BAX ActivatorBAM7, BAX Activator$109.00Catalog No. M60069The first potent and selective small molecule activator of BAX, which is a pro-apoptotic BCL-2 family member.BAY 87-2243, Hypoxia-inducible Factor-1 (HIF-1) InhibitorBAY 87-2243, Hypoxia-inducible Factor-1 (HIF-1) InhibitorBAY 87-2243, Hypoxia-inducible Factor-1 (HIF-1) Inhibitor$119.00Catalog No. M60217A highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.BAY11-7082, E2 Ubiquitin Conjugating Enzyme InhibitorBAY11-7082, E2 Ubiquitin Conjugating Enzyme InhibitorBAY11-7082, E2 Ubiquitin Conjugating Enzyme Inhibitor$89.00Catalog No. M60309A potent and selective E2 ubiquitin (Ub) conjugating enzyme inhibitor.BAZ2-ICR, BAZ2 Bromodomain InhibitorBAZ2-ICR, BAZ2 Bromodomain InhibitorBAZ2-ICR, BAZ2 Bromodomain Inhibitor$129.00Catalog No. M60226A potent and selective BAZ2 bromodomain inhibitor.BETP, GLP-1R PotentiatorBETP, GLP-1R PotentiatorBETP, GLP-1R Potentiator$129.00Catalog No. M60196A positive allosteric modulator and partial agonist of the glucagon-like peptide 1 (GLP-1) receptor.BG45, HDAC3 InhibitorBG45, HDAC3 InhibitorBG45, HDAC3 Inhibitor$59.00Catalog No. M60266A potent, selective and cell permeable HDAC3 inhibitor.BI-2536, PLK1 and BRD4 Dual Inhibitor BI-2536, PLK1 and BRD4 Dual InhibitorBI-2536, PLK1 and BRD4 Dual Inhibitor$119.00Catalog No. M60171BI-2536 is a potent inhibitor of PLK1 (Polo-like kinase 1) and BRD4 in clinical trials.BI-7273, BRD9 Bromodomain InhibitorBI-7273, BRD9 Bromodomain InhibitorBI-7273, BRD9 Bromodomain Inhibitor$129.00Catalog No. M60322A potent, selective and cell-permeable BRD9 inhibitor.BI-9564, BRD9 Bromodomain InhibitorBI-9564, BRD9 Bromodomain InhibitorBI-9564, BRD9 Bromodomain Inhibitor$129.00Catalog No. M60323A potent, selective and cell-permeable BRD9 inhibitor.BIBW2992(Afatinib), EGFR Inhibitor BIBW2992(Afatinib), EGFR InhibitorBIBW2992(Afatinib), EGFR Inhibitor$109.00Catalog No. M60065-5sA potent and selective irreversible inhibitor of EGFR/HER2 in clinical trials.Bioymifi, TRAIL Receptor DR5 ActivatorBioymifi, TRAIL Receptor DR5 ActivatorBioymifi, TRAIL Receptor DR5 Activator$109.00Catalog No. M60088A potent and selective small molecule agonist of DR5.BIX-01294, G9a/GLP HMTase InhibitorBIX-01294, G9a/GLP HMTase InhibitorBIX-01294, G9a/GLP HMTase Inhibitor$79.00Catalog No. M60216A potent and selective G9a and GLP histone lysine methyltransferase inhibitor.BMI1 Mouse Monoclonal AntibodyBMI1 Mouse Monoclonal AntibodyBMI1 Mouse Monoclonal Antibody$0.00Catalog No. A90010-5BMI1 Mouse Monoclonal Antibody.BMS-708163 (Avagacestat), -Secretase InhibitorBMS-708163 (Avagacestat), -Secretase InhibitorBMS-708163 (Avagacestat), -Secretase Inhibitor$89.00Catalog No. M60032A potent -secretase Inhibitor, more selective for APP than Notch, in clinical trials for Alzheimer s disease.BQU57, GTPase Ral InhibitorBQU57, GTPase Ral InhibitorBQU57, GTPase Ral Inhibitor$139.00Catalog No. M60228A potent and selective GTPase Ral InhibitorBRD9757, HDAC6 InhibitorBRD9757, HDAC6 InhibitorBRD9757, HDAC6 Inhibitor$129.00Catalog No. M60117A highly potent and selective HDAC6 inhibitor.Bromosporine, Pan-bromodomain InhibitorBromosporine, Pan-bromodomain InhibitorBromosporine, Pan-bromodomain Inhibitor$129.00Catalog No. M60144A broad spectrum inhibitor for bromodomains.C646, p300/CBP inhibitorC646, p300/CBP inhibitorC646, p300/CBP inhibitor$129.00Catalog No. M60129A potent, selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor.Carfilzomib, Proteasome InhibitorCarfilzomib, Proteasome InhibitorCarfilzomib, Proteasome Inhibitor$109.00Catalog No. M60109A selective, irreversible proteasome inhibitor.CASIN, Cdc42 Inhibitor CASIN, Cdc42 InhibitorCASIN, Cdc42 Inhibitor$139.00Catalog No. M60040A novel and potent inhibitor of Cdc42; was shown to rescue HSC aging phenotype and promote HSC transplantation efficiency.CAY10603, HDAC6 InhibitorCAY10603, HDAC6 InhibitorCAY10603, HDAC6 Inhibitor$129.00Catalog No. M60234A potent and selective HDAC6 inhibitor.CB-5083, p97 AAA ATPase Inhibitor CB-5083, p97 AAA ATPase InhibitorCB-5083, p97 AAA ATPase Inhibitor$129.00Catalog No. M60306A highly potent, selective and orally bioavailable p97 AAA ATPase inhibitor.CBX5 Polyclonal AntibodyCBX5 Polyclonal AntibodyCBX5 Polyclonal Antibody$0.00Catalog No. A70033Chromobox protein homolog 5CHIR99021, GSK3 Inhibitor CHIR99021, GSK3 InhibitorCHIR99021, GSK3 Inhibitor$390.00Catalog No. M60002 xcessbio公司品牌 总代理The most widely used, potent and selective GSK3 Inhibitor; Wnt pathway activator.CI994 (Tacedinaline), HDAC InhibitorCI994 (Tacedinaline), HDAC InhibitorCI994 (Tacedinaline), HDAC Inhibitor$59.00Catalog No. M60186A potent, selective and orally active histone deacetylase (HDAC) inhibitor targeting HDAC1, HDAC2 and HDAC3.Cilliobrevin D, AAA+ ATPase Motor Cytoplasmic Dynein Inhibitor Cilliobrevin D, AAA+ ATPase Motor Cytoplasmic Dynein InhibitorCilliobrevin D, AAA+ ATPase Motor Cytoplasmic Dynein Inhibitor$139.00Catalog No. M60041-2sA novel and specific inhibitor of the AAA+ ATPase motor cytoplasmic dynein; perturbs protein| trafficking within the primary cilium and affects other dynein-dependent processes, such as spindle pole focusing, kinetochore-microtubule attachment, melanosome aggregation and peroxisome motility in cultured cells.Compound Library of Bromodomain/BETCompound Library of Bromodomain/BETCompound Library of Bromodomain/BET$1150.00$1437.00Catalog No. LI30006Compound Library of Bromodomain/BET set is composed of 23 small molecules in separated vials.Compound Library of HDACCompound Library of HDACCompound Library of HDAC$700.00$850.00Catalog No. LI30005Compound Library of HDAC set is composed of 18 small molecules in separated vials.Compound Library of Histone DemethylaseCompound Library of Histone DemethylaseCompound Library of Histone Demethylase$1400.00Catalog No. LI30003Library of Histone Demethylase is composed of 15 small molecules in separated vials.Compound Library of Histone MethyltransferaseCompound Library of Histone MethyltransferaseCompound Library of Histone Methyltransferase$1200.00Catalog No. LI30002Compound Library of Histone Methyltransferase is composed of 14 small molecules in separated vials.Compound Library of Hypoxia Inducible FactorCompound Library of Hypoxia Inducible FactorCompound Library of Hypoxia Inducible Factor$360.00$446.00Catalog No. LI30007Epigenetic compounds library of Hypoxia Inducible FactorCP-690550, JAK InhibitorCP-690550, JAK InhibitorCP-690550, JAK Inhibitor$79.00Catalog No. M60033A potent and selective pan-JAK Inhibitor in clinical trials for rheumatoid arthritis.CPI-169, EZH2 Methyltransferase InhibitorCPI-169, EZH2 Methyltransferase InhibitorCPI-169, EZH2 Methyltransferase Inhibitor$129.00Catalog No. M60275A highly potent and selective small molecule inhibitor of histone methyltransferase EZH2.CPI-455, KDM5 Demethylases Inhibitor CPI-455, KDM5 Demethylases InhibitorCPI-455, KDM5 Demethylases Inhibitor$129.00Catalog No. M60326A potent and selective KDM inhibitor.CPI203, BET InhibitorCPI203, BET InhibitorCPI203, BET Inhibitor$139.00Catalog No. M60124A novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4, inhibiting Myc expression.CRISPR Editing Tool BoxCRISPR Editing Tool BoxCRISPR Editing Tool Box$499.00Catalog No. LI30010Compound collection for CRISPR editing.CTEP, mGlu5 AntagonistCTEP, mGlu5 AntagonistCTEP, mGlu5 Antagonist$259.00Catalog No. M60099A highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor.CUDC-101， HDAC/EGFR/HER2 Inhibitor CUDC-101， HDAC/EGFR/HER2 InhibitorCUDC-101， HDAC/EGFR/HER2 Inhibitor$69.00Catalog No. M60092A potent multi-target inhibitor targeting HDAC, EGFR and HER2 in clinical trial.CUDC-907, PI3K/HDAC dual inhibitorCUDC-907, PI3K/HDAC dual inhibitorCUDC-907, PI3K/HDAC dual inhibitor$139.00Catalog No. M60077A potent dual inhibitor of class I PI3K kinases and HDACs in clinical trials.Custom synthesis product 1Custom synthesis product 1Custom synthesis product 1$5000.00Catalog No. CS-1CX-4945, CK2 (Casein Kinase 2) InhibitorCX-4945, CK2 (Casein Kinase 2) InhibitorCX-4945, CK2 (Casein Kinase 2) Inhibitor$129.00Catalog No. M60267A potent, selective and bioavailable CK2 (Casein Kinase 2) Inhibitor.CX-5461, RNA Polymerase I inhibitorCX-5461, RNA Polymerase I inhibitorCX-5461, RNA Polymerase I inhibitor$149.00Catalog No. M66052A potent and selective RNA Polymerase I inhibitor, for anti-tumor use.Cyclopamine, Hedgehog AntagonistCyclopamine, Hedgehog AntagonistCyclopamine, Hedgehog Antagonist$79.00Catalog No. M60022A potent natural product of Hedgehog antagonist; directly binding to the Smoothened/Smo.Cyclosporin A, MPTP Inhibitor and HSC ProtectorCyclosporin A, MPTP Inhibitor and HSC ProtectorCyclosporin A, MPTP Inhibitor and HSC Protector$39.00Catalog No. M60262An inhibitor of the mitochondrial permeability transition pore (MPTP).Daidzein-2c, Osteogenic ModulatorDaidzein-2c, Osteogenic ModulatorDaidzein-2c, Osteogenic Modulator$109.00Catalog No. M60158A potent synthetic daidzein analog with osteogenic induction potentials on human Mesenchymal Stem Cells (MSC).Daminozide --- KDM2/7 Histone Demethylases InhibitorDaminozide --- KDM2/7 Histone Demethylases InhibitorDaminozide --- KDM2/7 Histone Demethylases Inhibitor$69.00Catalog No. M60074A potent and selective small molecule inhibitor of the KDM2/7 family of human JmjC histone demethylases.DAPT, -secretase InhibitorDAPT, -secretase InhibitorDAPT, -secretase Inhibitor$300.00Catalog No. M60023A -secretase inhibitor and widely used as a Notch pathway inhibitor.DASA-58 (ML203), Pyruvate Kinase M2 (PKM2) ActivatorDASA-58 (ML203), Pyruvate Kinase M2 (PKM2) ActivatorDASA-58 (ML203), Pyruvate Kinase M2 (PKM2) Activator$109.00Catalog No. M60305A potent and selective Pyruvate kinase M2 (PKM2) activator.Deltarasin, KRAS-PDE InhibitorDeltarasin, KRAS-PDE InhibitorDeltarasin, KRAS-PDE Inhibitor$139.00Catalog No. M60218A potent and selective small molecular inhibitor of KRAS-PDE interactiondemodemodemo$0.00Catalog No. 123456DMOG, Prolyl 4-hydroxylase (P4H) InhibitorDMOG, Prolyl 4-hydroxylase (P4H) InhibitorDMOG, Prolyl 4-hydroxylase (P4H) Inhibitor$39.00Catalog No. M60287A selective, competitive and cell permeable prolyl 4-hydroxylase (P4H) inhibitor.DMXAA (Vadimezan), mSTING AgonistDMXAA (Vadimezan), mSTING AgonistDMXAA (Vadimezan), mSTING Agonist$79.00Catalog No. M60301A potent and selective mSTING agonist, selective for mouse STING over human STING.DNMT3A Polyclonal AntibodyDNMT3A Polyclonal AntibodyDNMT3A Polyclonal Antibody$0.00Catalog No. A70035DNA (cytosine-5)-methyltransferase 3A (DNMT3A)DZNep (3-Deazaneplanocin A) --- Histone Methyltransferase Inhibitor DZNep (3-Deazaneplanocin A) --- Histone Methyltransferase InhibitorDZNep (3-Deazaneplanocin A) --- Histone Methyltransferase Inhibitor$129.00Catalog No. M60141An S-adenosylhomocysteine hydrolase inhibitor, indirectly inhibiting histone methyltransferases and decreasing global DNA methylationEED226, PRC2 InhibitorEED226, PRC2 InhibitorEED226, PRC2 Inhibitor$139.00Catalog No. M60327A potent and selective allosteric PRC2 inhibitor that directly binds to the H3K27me3 binding pocket of EED.EML425, CBP/p300 InhibitorEML425, CBP/p300 InhibitorEML425, CBP/p300 Inhibitor$129.00Catalog No. M60257A selective, noncompetitive and cell permeable KAT3 histone acetyltransferases CBP/p300 inhibitor.Entinostat (MS-275) -- HDAC Inhibitor Entinostat (MS-275) -- HDAC InhibitorEntinostat (MS-275) -- HDAC Inhibitor$59.00Catalog No. M60174Entinostat (MS-275) is a potent and selective HDAC1 and HDAC3 inhibitor.EPZ-5676 --- DOT1L inhibitorEPZ-5676 --- DOT1L inhibitorEPZ-5676 --- DOT1L inhibitor$139.00Catalog No. M60123A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.EPZ-6438, EZH2 Methyltransferase InhibitorEPZ-6438, EZH2 Methyltransferase InhibitorEPZ-6438, EZH2 Methyltransferase Inhibitor$129.00Catalog No. M60122EPZ-6438 (E7438) is a potent and selective small molecule inhibitor of histone methyltransferase EZH2 in clinical development.EPZ015666 (GSK3235025), PRMT5 Inhibitor EPZ015666 (GSK3235025), PRMT5 InhibitorEPZ015666 (GSK3235025), PRMT5 Inhibitor$129.00Catalog No. M60254A potent, selective and orally bioavailable Protein arginine methyltransferase-5 (PRMT5) Inhibitor.EX-527, SIRT1 InhibitorEX-527, SIRT1 InhibitorEX-527, SIRT1 Inhibitor$69.00Catalog No. M60108EX-527 is a highly potent and selective inhibitor of SIRT1 with an IC50 ~98 nM.EZH2 Polyclonal AntibodyEZH2 Polyclonal AntibodyEZH2 Polyclonal Antibody$0.00Catalog No. A70036Histone-lysine N-methyltransferase EZH2FASCIN-G2, Fascin InhibitorFASCIN-G2, Fascin InhibitorFASCIN-G2, Fascin Inhibitor$129.00Catalog No. M60269A potent, selective and bioavailable small molecule that inhibits the actin-bundling activity of fascin.Fatostatin A, Sterol Regulatory Binding Proteins (SREBPs) InhibitorFatostatin A, Sterol Regulatory Binding Proteins (SREBPs) InhibitorFatostatin A, Sterol Regulatory Binding Proteins (SREBPs) Inhibitor$59.00Catalog No. M60180Fatostatin A is a highly potent, specific and cell permeable inhibitor of Sterol Regulatory Binding Proteins (SREBPs).Ferrostatin-1 (Fer-1), Ferroptosis Inhibitor Ferrostatin-1 (Fer-1), Ferroptosis InhibitorFerrostatin-1 (Fer-1), Ferroptosis Inhibitor$109.00Catalog No. M60042Ferrostatin-1 (Fer-1) is a potent inhibitor of ferroptosis with an EC50 ~60 nM, identified by a HTS using erastin-induced ferroptosis in HT-1080 cells.FG-4592 (Roxadustat), HIF Prolyl-Hydroxylases InhibitorFG-4592 (Roxadustat), HIF Prolyl-Hydroxylases InhibitorFG-4592 (Roxadustat), HIF Prolyl-Hydroxylases Inhibitor$39.00Catalog No. M60263A potent, selective and bioavailable inhibitor of hypoxia-inducible factor prolyl hydroxylase.FH1, Hepatocytes Functional EnhancerFH1, Hepatocytes Functional EnhancerFH1, Hepatocytes Functional Enhancer$139.00Catalog No. M60127FH1 is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC-derived hepatocytes toward a more mature phenotype in vitro.FLI-06, Notch Pathway ModulatorFLI-06, Notch Pathway ModulatorFLI-06, Notch Pathway Modulator$139.00Catalog No. M60149FLI-06 is a novel potent and selective small molecule intercepting Notch signaling and the early secretory pathway (EC50 ~2.3 µM), identified by using automated microscopy to monitor the trafficking and processing of a ligand-independent Notch-GFP fusion reporter.Fmoc-Ala-Ala-Asn-PAB-PNPFmoc-Ala-Ala-Asn-PAB-PNPFmoc-Ala-Ala-Asn-PAB-PNPInquiryCatalog No. L60002Peptide prodrug linkerFmoc-Val-Cit-PABFmoc-Val-Cit-PABFmoc-Val-Cit-PABInquiryCatalog No. L60001Peptide prodrug linkerForskolin, Adenylyl Cyclase Activator Forskolin, Adenylyl Cyclase ActivatorForskolin, Adenylyl Cyclase Activator$79.00Catalog No. M60024A potent adenylate cyclase activator to increase the in|tracellular levels of cAMP.FPH1, Hepatocytes Functional Proliferation InducerFPH1, Hepatocytes Functional Proliferation InducerFPH1, Hepatocytes Functional Proliferation Inducer$139.00Catalog No. M60126FPH1 is a potent and selective small molecule that induced Functional Proliferation of primary human Hepatocytes in vitro, identified by a high-throughput, cell-based screening using primary human hepatocytes.Furamidine, PRMT1 InhibitorFuramidine, PRMT1 InhibitorFuramidine, PRMT1 Inhibitor$99.00Catalog No. M60256A potent, selective and cell permeable Protein arginine methyltransferase-1 (PRMT1) inhibitor.GDC-0068, Akt Inhibitor GDC-0068, Akt InhibitorGDC-0068, Akt Inhibitor$159.00Catalog No. M60066A novel potent and selective ATP competitive Akt inhibitor in clinical trials.GDC-0349, mTOR Inhibitor GDC-0349, mTOR InhibitorGDC-0349, mTOR Inhibitor$129.00Catalog No. M60110A potent and selective ATP-competitive inhibitor of mTOR in clinical trials.GDC-0449 (Vismodegib), Hedgehog Antagonist GDC-0449 (Vismodegib), Hedgehog AntagonistGDC-0449 (Vismodegib), Hedgehog Antagonist$79.00Catalog No. M60034A potent and specific hedgehog pathway inhibitor approved by FDAGDC-0941, PI3K Inhibitor GDC-0941, PI3K InhibitorGDC-0941, PI3K Inhibitor$79.00Catalog No. M60111A highly potent, selective and orally bioavailable class-I PI3K kinase inhibitor.GN44028, HIF-1 InhibitorGN44028, HIF-1 InhibitorGN44028, HIF-1 Inhibitor$89.00Catalog No. M60325A potent and selective HIF-1 inhibitor.GNF-7, Ras Signaling InhibitorGNF-7, Ras Signaling InhibitorGNF-7, Ras Signaling Inhibitor$129.00Catalog No. M60281A potent, selective and bioavailable Ras signaling inhibitor.GNF4877, Cell Proliferation Inducer GNF4877, Cell Proliferation InducerGNF4877, Cell Proliferation Inducer$159.00Catalog No. M60294A highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets.GNF7156, Cell Proliferation Inducer GNF7156, Cell Proliferation InducerGNF7156, Cell Proliferation Inducer$139.00Catalog No. M60293A highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets.Go6893, PKC InhibitorGo6893, PKC InhibitorGo6893, PKC Inhibitor$129.00Catalog No. M60273A potent pan-PKC inhibitor.GPR39-C3, GPR39 AgonistGPR39-C3, GPR39 AgonistGPR39-C3, GPR39 Agonist$139.00Catalog No. M60209The first potent, selective and orally bioavailable GPR39 agonist.GPR39-C3bulkGPR39-C3bulkGPR39-C3bulk$0.00$875.00Catalog No. M60209-bGS143, IkappaB Ubiquitination Inhibitor GS143, IkappaB Ubiquitination InhibitorGS143, IkappaB Ubiquitination Inhibitor$129.00Catalog No. M60308A selective -TrCP1 ligase inhibitorGSK-J1, H3K27 Histone Demethylases UTX and JMJD3 Inhibitor GSK-J1, H3K27 Histone Demethylases UTX and JMJD3 InhibitorGSK-J1, H3K27 Histone Demethylases UTX and JMJD3 Inhibitor$109.00Catalog No. M60062The first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3.GSK-J4, H3K27 Histone Demethylases UTX and JMJD3 Inhibitor GSK-J4, H3K27 Histone Demethylases UTX and JMJD3 InhibitorGSK-J4, H3K27 Histone Demethylases UTX and JMJD3 Inhibitor$109.00Catalog No. M60063An ethyl ester derivative of GSK-J1 as a pro-drug for cellular assays; the first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3.GSK-J4bulkGSK-J4bulkGSK-J4bulk$0.00Catalog No. M60063-bGSK-LSD1, LSD1 InhibitorGSK-LSD1, LSD1 InhibitorGSK-LSD1, LSD1 Inhibitor$139.00Catalog No. M60179A highly potent, specific and irreversible inhibitor of Lysine Specific Demethylase-1 (LSD1).GSK126, EZH2 Methyltransferase Inhibitor.GSK126, EZH2 Methyltransferase Inhibitor.GSK126, EZH2 Methyltransferase Inhibitor.$129.00Catalog No. M60071GSK126 is a highly potent and selective small molecule inhibitor of histone methyltransferase EZH2.GSK126bulkGSK126bulkGSK126bulk$0.00Catalog No. M60071-bGSK2801, Bromodomain BAZ2A/B InhibitorGSK2801, Bromodomain BAZ2A/B InhibitorGSK2801, Bromodomain BAZ2A/B Inhibitor$129.00Catalog No. M60283A potent, selective and cell permeable inhibitor of the bromodomain BAZ2A and BAZ2B.GSK2879552, LSD1 InhibitorGSK2879552, LSD1 InhibitorGSK2879552, LSD1 Inhibitor$129.00Catalog No. M60297A highly potent, selective and orally bioavailable irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1).GSK343, EZH2 Methyltransferase InhibitorGSK343, EZH2 Methyltransferase InhibitorGSK343, EZH2 Methyltransferase Inhibitor$79.00Catalog No. M60173GSK343 is a potent and selective small molecule inhibitor of histone methyltransferase EZH2.GSK591 (EPZ015866), PRMT5 InhibitorGSK591 (EPZ015866), PRMT5 InhibitorGSK591 (EPZ015866), PRMT5 Inhibitor$109.00Catalog No. M60321A potent and selective Protein arginine methyltransferase-5 (PRMT5) Inhibitor.GSK5959, BRPF1 Bromodomain InhibitorGSK5959, BRPF1 Bromodomain InhibitorGSK5959, BRPF1 Bromodomain Inhibitor$129.00Catalog No. M60239A potent, selective and cell permeable BRPF1 bromodomain inhibitor.H3K36me3 Mouse Monoclonal AntibodyH3K36me3 Mouse Monoclonal AntibodyH3K36me3 Mouse Monoclonal Antibody$0.00Catalog No. A90004H3K36me3 Mouse Monoclonal AntibodyH3K4me1 Polyclonal AntibodyH3K4me1 Polyclonal AntibodyH3K4me1 Polyclonal AntibodyInquiryCatalog No. A70010Monomethylated H3K4 Polyclonal AntibodyH3K4me3 Mouse Monoclonal AntibodyH3K4me3 Mouse Monoclonal AntibodyH3K4me3 Mouse Monoclonal AntibodyInquiryCatalog No. A90006H3K4me3 Mouse Monoclonal AntibodyH3K79me1 Mouse Monoclonal AntibodyH3K79me1 Mouse Monoclonal AntibodyH3K79me1 Mouse Monoclonal AntibodyInquiryCatalog No. A90001H3K79me1 Mouse Monoclonal AntibodyH3K79me2 Mouse Monoclonal AntibodyH3K79me2 Mouse Monoclonal AntibodyH3K79me2 Mouse Monoclonal AntibodyInquiryCatalog No. A90002H3K79me2 Mouse Monoclonal AntibodyH3K79me3 Mouse Monoclonal AntibodyH3K79me3 Mouse Monoclonal AntibodyH3K79me3 Mouse Monoclonal AntibodyInquiryCatalog No. A90003H3K79me3 Mouse Monoclonal AntibodyH3K9(Ac)K14(Ac) Rabbit pAbH3K9(Ac)K14(Ac) Rabbit pAbH3K9(Ac)K14(Ac) Rabbit pAb$250.00Catalog No. A-10001-100H3K9me3 Mouse Monoclonal AntibodyH3K9me3 Mouse Monoclonal AntibodyH3K9me3 Mouse Monoclonal AntibodyInquiryCatalog No. A90005H3K9me3 Mouse Monoclonal AntibodyHarmine, DYRK1A InhibitorHarmine, DYRK1A InhibitorHarmine, DYRK1A Inhibitor$29.00Catalog No. M60241A potent, selective and orally bioavailable DYRK1A inhibitor.HBX41108, USP7 InhibitorHBX41108, USP7 InhibitorHBX41108, USP7 Inhibitor$129.00Catalog No. M60244A potent and selective ubiquitin-specific protease 7 (USP7) inhibitor.HCI-2509 (SP2509), Reversible LSD1 Inhibitor.HCI-2509 (SP2509), Reversible LSD1 Inhibitor.HCI-2509 (SP2509), Reversible LSD1 Inhibitor.$109.00Catalog No. M60160A highly potent, specific, and reversible Lysine Specific Demethylase-1 (LSD1) inhibitor with in vivo efficacy.HDAC4 Mouse Monoclonal AntibodyHDAC4 Mouse Monoclonal AntibodyHDAC4 Mouse Monoclonal AntibodyInquiryCatalog No. A90011Histone deacetylase 4 (HDAC4) is a histone deacetylase that represses transcription when tethered to a promoter.HDAC4 Polyclonal AntibodyHDAC4 Polyclonal AntibodyHDAC4 Polyclonal AntibodyInquiryCatalog No. A70037Histone deacetylase 4Heclin, HECT E3 Ubiquitin Ligase InhibitorHeclin, HECT E3 Ubiquitin Ligase InhibitorHeclin, HECT E3 Ubiquitin Ligase Inhibitor$89.00Catalog No. M60248A selective HECT E3 ubiquitin ligase inhibitor to inhibit Nedd4, Smurf2 and WWP1.HG-10-102-01, LRRK2 Inhibitor HG-10-102-01, LRRK2 InhibitorHG-10-102-01, LRRK2 Inhibitor$139.00Catalog No. M60061A brain penetrant potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant.Hh-Ag1.5, Hedgehog Agonist Hh-Ag1.5, Hedgehog AgonistHh-Ag1.5, Hedgehog Agonist$139.00Catalog No. M60004The most potent and selective agonist of the Hh pathway (Smoothened/Smo agonist); could replace the recombinant Hh protein to activate the Hh pathwayHIF-C2, HIF-2 Inhibitor HIF-C2, HIF-2 InhibitorHIF-C2, HIF-2 Inhibitor$139.00Catalog No. M60121A potent and selective allosteric inhibitor of hypoxia inducible factor-2 (HIF-2).Histone H3K27me1 Polyclonal AntibodyHistone H3K27me1 Polyclonal AntibodyHistone H3K27me1 Polyclonal AntibodyInquiryCatalog No. A70013histone H3 containing the monomethylated lysine 27Histone H3K27me2 Polyclonal AntibodyHistone H3K27me2 Polyclonal AntibodyHistone H3K27me2 Polyclonal AntibodyInquiryCatalog No. A70014histone H3 containing the dimethylated lysine 27Histone H3K27me3 Polyclonal AntibodyHistone H3K27me3 Polyclonal AntibodyHistone H3K27me3 Polyclonal AntibodyInquiryCatalog No. A70015histone H3 containing the trimethylated lysine 27Histone H3K36me1 Polyclonal AntibodyHistone H3K36me1 Polyclonal AntibodyHistone H3K36me1 Polyclonal AntibodyInquiryCatalog No. A70016histone H3 containing the monomethylated lysine 36Histone H3K36me2 Polyclonal AntibodyHistone H3K36me2 Polyclonal AntibodyHistone H3K36me2 Polyclonal AntibodyInquiryCatalog No. A70017histone H3 containing the dimethylated lysine 36Histone H3K36me3 Polyclonal AntibodyHistone H3K36me3 Polyclonal AntibodyHistone H3K36me3 Polyclonal AntibodyInquiryCatalog No. A70018histone H3 containing the trimethylated lysine 36Histone H3K4me2 Polyclonal AntibodyHistone H3K4me2 Polyclonal AntibodyHistone H3K4me2 Polyclonal AntibodyInquiryCatalog No. A70011histone H3 containing the dimethylated lysine 4Histone H3K4me3 Polyclonal AntibodyHistone H3K4me3 Polyclonal AntibodyHistone H3K4me3 Polyclonal AntibodyInquiryCatalog No. A70012histone H3 containing the trimethylated lysine 4Histone H3K79me1 Polyclonal AntibodyHistone H3K79me1 Polyclonal AntibodyHistone H3K79me1 Polyclonal AntibodyInquiryCatalog No. A70019histone H3 containing the monomethylated lysine 79Histone H3K79me2 Polyclonal AntibodyHistone H3K79me2 Polyclonal AntibodyHistone H3K79me2 Polyclonal AntibodyInquiryCatalog No. A70020histone H3 containing the dimethylated lysine 79Histone H3K79me3 Polyclonal AntibodyHistone H3K79me3 Polyclonal AntibodyHistone H3K79me3 Polyclonal AntibodyInquiryCatalog No. A70021histone H3 containing the trimethylated lysine 79Histone H3K9me1 Polyclonal AntibodyHistone H3K9me1 Polyclonal AntibodyHistone H3K9me1 Polyclonal AntibodyInquiryCatalog No. A70022histone H3 containing the monomethylated lysine 9Histone H3K9me2 Polyclonal AntibodyHistone H3K9me2 Polyclonal AntibodyHistone H3K9me2 Polyclonal AntibodyInquiryCatalog No. A70023histone H3 containing the dimethylated lysine 9Histone H3K9me3 Polyclonal AntibodyHistone H3K9me3 Polyclonal AntibodyHistone H3K9me3 Polyclonal AntibodyInquiryCatalog No. A70024histone H3 containing the trimethylated lysine 9Histone H3R26me1 Polyclonal AntibodyHistone H3R26me1 Polyclonal AntibodyHistone H3R26me1 Polyclonal AntibodyInquiryCatalog No. A70031histone H3 containing the monomethylated Arg26Histone H3R26me2a Polyclonal AntibodyHistone H3R26me2a Polyclonal AntibodyHistone H3R26me2a Polyclonal AntibodyInquiryCatalog No. A70032histone H3 containing the asymmetrically dimethylated Arg26Histone H3R2me1 Polyclonal AntibodyHistone H3R2me1 Polyclonal AntibodyHistone H3R2me1 Polyclonal AntibodyInquiryCatalog No. A70029histone H3 containing the monomethylated Arg2Histone H3R2me2a Polyclonal AntibodyHistone H3R2me2a Polyclonal AntibodyHistone H3R2me2a Polyclonal AntibodyInquiryCatalog No. A70028histone H3 containing the asymmetrically dimethylated Arg2Histone H3R2me2s Polyclonal AntibodyHistone H3R2me2s Polyclonal AntibodyHistone H3R2me2s Polyclonal AntibodyInquiryCatalog No. A70030histone H3 containing the symmetrically dimethylated Arg2Histone H4R3me1 Polyclonal AntibodyHistone H4R3me1 Polyclonal AntibodyHistone H4R3me1 Polyclonal AntibodyInquiryCatalog No. A70025histone H4 containing the monomethylated Arg3Histone H4R3me2a Polyclonal AntibodyHistone H4R3me2a Polyclonal AntibodyHistone H4R3me2a Polyclonal AntibodyInquiryCatalog No. A70027histone H4 containing the asymmetrically dimethylated Arg3Histone H4R3me2s Polyclonal AntibodyHistone H4R3me2s Polyclonal AntibodyHistone H4R3me2s Polyclonal AntibodyInquiryCatalog No. A70026histone H4 containing the symmetrically dimethylated Arg3HLCL-61, PRMT5 InhibitorHLCL-61, PRMT5 InhibitorHLCL-61, PRMT5 Inhibitor$109.00Catalog No. M60320A potent and selective Protein arginine methyltransferase-5 (PRMT5) Inhibitor.HLY78, Wnt ActivatorHLY78, Wnt ActivatorHLY78, Wnt Activator$149.00Catalog No. M60140An activator of the Wnt pathway by targeting the DIX domain of Axin and potentiating the Axin LRP6 association, thus promoting LRP6 phosphorylation and Wnt signaling transduction.HPOB, HDAC6 InhibitorHPOB, HDAC6 InhibitorHPOB, HDAC6 Inhibitor$79.00Catalog No. M60231A potent and selective HDAC6 inhibitor.Hydroxychloroquine (HCQ), Autophagy and TLR9 Inhibitor Hydroxychloroquine (HCQ), Autophagy and TLR9 InhibitorHydroxychloroquine (HCQ), Autophagy and TLR9 Inhibitor$49.00Catalog No. M60302A potent autophagy inhibitor and TLR9 inhibitorI-BET151 (GSK1210151A), BET Inhibitor I-BET151 (GSK1210151A), BET InhibitorI-BET151 (GSK1210151A), BET Inhibitor$109.00Catalog No. M66053A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4.I-BET762 (GSK525762), BET Inhibitor I-BET762 (GSK525762), BET InhibitorI-BET762 (GSK525762), BET Inhibitor$139.00Catalog No. M60154A novel, highly potent, selective and cell permeable BET inhibitor in clinical trials.I-BRD9, Bromodomain Containing Protein 9 (BRD9) InhibitorI-BRD9, Bromodomain Containing Protein 9 (BRD9) InhibitorI-BRD9, Bromodomain Containing Protein 9 (BRD9) Inhibitor$129.00Catalog No. M60276A potent, selective and cell permeable Bromodomain Containing Protein 9 (BRD9) inhibitor.I-CBP112, p300/CBP Bromodomain Inhibitor I-CBP112, p300/CBP Bromodomain InhibitorI-CBP112, p300/CBP Bromodomain Inhibitor$139.00Catalog No. M60128A highly potent and selective p300/CBP bromodomain inhibitor.ID-8, DYRK| InhibitorID-8, DYRK| InhibitorID-8, DYRK| Inhibitor$89.00Catalog No. M60102A potent and selective small molecule inhibitor of dual-specificity tyrosine phosphorylation- regulated kinase (DYRK).IDH-C227, IDH1 Inhibitor IDH-C227, IDH1 InhibitorIDH-C227, IDH1 Inhibitor$139.00Catalog No. M60043A potent and selective inhibitor of the IDH1 R132H mutant with good cellular activity.IDH2-C100, IHD2 Inhibitor IDH2-C100, IHD2 InhibitorIDH2-C100, IHD2 Inhibitor$129.00Catalog No. M60190A potent and selective inhibitor of IDH2 R140Q and R172K mutant.IDH2-C100BulkIDH2-C100BulkIDH2-C100Bulk$750.00$990.00Catalog No. M60190-biN-LSCiN-LSCiN-LSC$89.00Catalog No. S10004Combination of LDN193189 (BMP inhibitor), SB431542 (TGF inhibitor), and CHIR99021 (GSK3 inhibitor) can enhance reprogramming of human fibroblasts into induced neurons.INCB024360 (Epacadostat), IDO InhibitorINCB024360 (Epacadostat), IDO InhibitorINCB024360 (Epacadostat), IDO Inhibitor$109.00Catalog No. M60292A potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor.INDY, DYRK1A/B InhibitorINDY, DYRK1A/B InhibitorINDY, DYRK1A/B Inhibitor$79.00Catalog No. M60242A potent and selective DYRK1A/B inhibitor.IOX1, 2OG Oxygenases InhibitorIOX1, 2OG Oxygenases InhibitorIOX1, 2OG Oxygenases Inhibitor$109.00Catalog No. M60195A cell-permeable broad-spectrum inhibitor of most 2OG oxygenases.IOX2, HIF Prolyl-Hydroxylases (PHD2) Inhibitor IOX2, HIF Prolyl-Hydroxylases (PHD2) InhibitorIOX2, HIF Prolyl-Hydroxylases (PHD2) Inhibitor$89.00Catalog No. M66054A potent and selective PHD (HIF prolyl-hydroxylases) inhibitor with cellular activity.IOX4, PHD2 InhibitorIOX4, PHD2 InhibitorIOX4, PHD2 Inhibitor$109.00Catalog No. M60284A potent and selective PHD2 inhibitor.iPSC-TSPCiPSC-TSPCiPSC-TSPC$109.00Catalog No. S10005Combination of Thiazovivin (ROCK inhibitor), SB431542 (TGF inhibitor), PD0325901 (MEK inhibitor), and CHIR99021 (GSK3 inhibitor) can enhance and accelerate reprogramming of human somatic cells (e.g., fibroblasts) into iPSCs.IRE-3, IRE1a Modulator IRE-3, IRE1a ModulatorIRE-3, IRE1a Modulator$129.00Catalog No. M60167A highly potent and selective small molecule modulator of IRE1 .Ischemin, CBP Bromodomain Inhibitor Ischemin, CBP Bromodomain InhibitorIschemin, CBP Bromodomain Inhibitor$79.00Catalog No. M60229A potent, selective and cell permeable CBP bromodomain inhibitor.ISRIB (trans-isomer), Inhibitor of Integrated Stress Response (ISR)ISRIB (trans-isomer), Inhibitor of Integrated Stress Response (ISR)ISRIB (trans-isomer), Inhibitor of Integrated Stress Response (ISR)$129.00Catalog No. M60125A potent and selective small molecule inhibitor of PERK signaling that can potently reverse the effects of eIF2 phosphorylation, Inhibitor of Integrated Stress Response (ISR).ISX9, Neurogenic ModulatorISX9, Neurogenic ModulatorISX9, Neurogenic Modulator$99.00Catalog No. M60274A neurogenic modulator.ITD-1, TGF inhibitor ITD-1, TGF inhibitorITD-1, TGF inhibitor$139.00Catalog No. M60060A highly selective TGF inhibitor promotes cardiomyogenesis in embryonic stem cells.IU1, Proteasome USP14 Inhibitor IU1, Proteasome USP14 InhibitorIU1, Proteasome USP14 Inhibitor$49.00Catalog No. M60203A cell-permeable, reversible and selective inhibitor of human proteasome USP14.IWP-2, Porcupine (Wnt) Inhibitor IWP-2, Porcupine (Wnt) InhibitorIWP-2, Porcupine (Wnt) Inhibitor$79.00Catalog No. M60115A potent and highly selective Wnt signaling antagonist targeting porcupine.J147, Neuroprotective Small MoleculeJ147, Neuroprotective Small MoleculeJ147, Neuroprotective Small Molecule$89.00Catalog No. M60012A potent and orally active neurotrophic molecule with broadly neuroprotective efficacy in vitro and in vivo.JIB-04 (NSC693627), Jumonji Histone Demethylase InhibitorJIB-04 (NSC693627), Jumonji Histone Demethylase InhibitorJIB-04 (NSC693627), Jumonji Histone Demethylase Inhibitor$119.00Catalog No. M60132A potent, selective and cell permeable Jumonji histone demethylase inhibitor, not a competitive inhibitor of a-ketoglutarate.JK184, Hedgehog Antagonist JK184, Hedgehog AntagonistJK184, Hedgehog Antagonist$79.00Catalog No. M60087A potent and cell-permeable inhibitor of hedgehog (Hh) signaling downstream of Smo.JNJ-42041935, HIF-PHD InhibitorJNJ-42041935, HIF-PHD InhibitorJNJ-42041935, HIF-PHD Inhibitor$129.00Catalog No. M60285A potent and selective HIF-PHD inhibitor.Kartogenin (KGN), Chondrogenesis Modulator Kartogenin (KGN), Chondrogenesis ModulatorKartogenin (KGN), Chondrogenesis Modulator$79.00Catalog No. M60027Selectively promote chondrocyte differentiation of human mesenchymal stem cells.KDM5 C70bulkKDM5 C70bulkKDM5 C70bulk$0.00Catalog No. M60192-bKDM5-C49, JARID1 Histone Demethylases Inhibitor KDM5-C49, JARID1 Histone Demethylases InhibitorKDM5-C49, JARID1 Histone Demethylases Inhibitor$139.00Catalog No. M60191A potent and selective inhibitor of Jumonji AT-Rich Interactive Domain 1 (JARID1) histone demethylasesKDM5-C49bulkKDM5-C49bulkKDM5-C49bulk$0.00Catalog No. M60191-bKDM5-C70, JARID1 Histone Demethylases Inhibitor KDM5-C70, JARID1 Histone Demethylases InhibitorKDM5-C70, JARID1 Histone Demethylases Inhibitor$139.00Catalog No. M60192An ethyl ester derivative of KDM5-C49, which is a potent and selective inhibitor of Jumonji AT-Rich Interactive Domain 1 (JARID1) histone demethylases.KL001, Cryptochrome ActivatorKL001, Cryptochrome ActivatorKL001, Cryptochrome Activator$79.00Catalog No. M66044A novel small molecule specifically interacting with cryptochrome (CRY) and causing lengthening of the circadian period.KRAS-C9, K-Ras(G12C) Inhibitor KRAS-C9, K-Ras(G12C) InhibitorKRAS-C9, K-Ras(G12C) Inhibitor$139.00Catalog No. M60219A potent and selective allosteric inhibitor of oncogenic K-Ras(G12C).KY02111, Wnt Inhibitor KY02111, Wnt InhibitorKY02111, Wnt Inhibitor$109.00Catalog No. M60073A potent and selective Wnt inhibitor promotes differentiation of hESCs/iPSCs to cardiomyocytes; might function downstream from GSK3 and APC in b-catenin destruction complexKYA1797K, Wnt/ -catenin InhibitorKYA1797K, Wnt/ -catenin InhibitorKYA1797K, Wnt/ -catenin Inhibitor$129.00Catalog No. M60317A highly potent and selective Wnt/ -catenin inhibitor binding directly to the regulators of G-protein signaling domain of axin.L002 (NSC764414), p300 Inhibitor L002 (NSC764414), p300 InhibitorL002 (NSC764414), p300 Inhibitor$99.00Catalog No. M60198A novel selective, cell permeable and reversible inhibitor of p300 histone acetyl transferase.L755,507, CRISPR Editing EnhancerL755,507, CRISPR Editing EnhancerL755,507, CRISPR Editing Enhancer$89.00Catalog No. M60237CRISPR editing enhancer to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs) and other cell types.LDE225, Hedgehog Antagonist LDE225, Hedgehog AntagonistLDE225, Hedgehog Antagonist$99.00Catalog No. M60013A potent and specific Hedgehog pathway inhibitor (Smo antagonist) in clinical trials.LDN-193189, BMP inhibitor LDN-193189, BMP inhibitorLDN-193189, BMP inhibitor$79.00Catalog No. M60008A highly potent and selective BMP pathway inhibitor (selective for ALK2 and ALK3); can replace Noggin protein in cellular and in vivo use.LDN-57444, Ubiquitin C-terminal Hydrolase-L1 (UCH-L1) InhibitorLDN-57444, Ubiquitin C-terminal Hydrolase-L1 (UCH-L1) InhibitorLDN-57444, Ubiquitin C-terminal Hydrolase-L1 (UCH-L1) Inhibitor$69.00Catalog No. M60204A novel potent and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1).LGK974, Porcupine (Wnt) Inhibitor LGK974, Porcupine (Wnt) InhibitorLGK974, Porcupine (Wnt) Inhibitor$139.00Catalog No. M60106A highly potent, selective and orally bioavailable Porcupine inhibitor (Wnt signaling antagonist) in clinical trials.Library of Epigenetic compoundsLibrary of Epigenetic compoundsLibrary of Epigenetic compounds$7000.00Catalog No. LI30001-2Compound Library of Epigenetic Set is composed of 117 small molecules in separated vials.LLY-507, Protein-lysine Methyltransferase SMYD2 InhibitorLLY-507, Protein-lysine Methyltransferase SMYD2 InhibitorLLY-507, Protein-lysine Methyltransferase SMYD2 Inhibitor$129.00Catalog No. M60259A potent, selective and cell permeable protein lysine methyltransferase SMYD2 inhibitor.LMK235, HDAC4 and HDAC5 Inhibitor LMK235, HDAC4 and HDAC5 InhibitorLMK235, HDAC4 and HDAC5 Inhibitor$89.00Catalog No. M60145A potent and selective histone deacetylase HDAC4 and HDAC5 inhibitor.LSD1-C76, LSD1 Inhibitor LSD1-C76, LSD1 InhibitorLSD1-C76, LSD1 Inhibitor$159.00Catalog No. M66045The most potent and selective Lysine Specific Demethylase-1 (LSD1) inhibitor so far.LY2109761, TGF InhibitorLY2109761, TGF InhibitorLY2109761, TGF Inhibitor$109.00Catalog No. M60035A novel potent and selective TGF receptor type I and type II (T RI/II) dual inhibitor with Ki of 38 nM and 300 nM respectively.LY2157299, TGF Inhibitor LY2157299, TGF InhibitorLY2157299, TGF Inhibitor$169.00Catalog No. M60064A novel potent and selective TGF receptor type I and type II (T RI/II) inhibitor with IC50 of 86 nM and 2 nM respectively.LY2784544, JAK2 inhibitorLY2784544, JAK2 inhibitorLY2784544, JAK2 inhibitor$129.00Catalog No. M60079A highly potent and selective mutant JAK2 (V617F) inhibitor.LY294002, PI3K/BET Dual Inhibitor LY294002, PI3K/BET Dual InhibitorLY294002, PI3K/BET Dual Inhibitor$79.00Catalog No. M60157A potent and selective small molecule PI3K and BET bromodomain dual inhibitor.LY411575, -secretase Inhibitor LY411575, -secretase InhibitorLY411575, -secretase Inhibitor$119.00Catalog No. M60078A highly potent, selective, and orally bioavailable inhibitor of gamma secretase.MAL-di-EG-OSuMAL-di-EG-OSuMAL-di-EG-OSu$0.00Catalog No. L600010Thiol reactive linkerMAL-HA-OSuMAL-HA-OSuMAL-HA-OSuInquiryCatalog No. L60005Thiol reactive linkerMALT1-MI-2 (MI-2), MALT1 inhibitor MALT1-MI-2 (MI-2), MALT1 inhibitorMALT1-MI-2 (MI-2), MALT1 inhibitor$129.00Catalog No. M60098A highly potent and selective small molecule directly binding to MALT1 and irreversibly suppressing its protease function.MC1568, Class IIa HDAC InhibitorMC1568, Class IIa HDAC InhibitorMC1568, Class IIa HDAC Inhibitor$79.00Catalog No. M60224A potent and selective inhibitor of class IIa histone deacetylases (HDACs), more selective for HD1-A than HD1-B.ME0328, PARP-3 InhibitorME0328, PARP-3 InhibitorME0328, PARP-3 Inhibitor$109.00Catalog No. M60329A potent, selective and cell permeable PARP-3 inhibitor.MEK162 (ARRY-162), MEK InhibitorMEK162 (ARRY-162), MEK InhibitorMEK162 (ARRY-162), MEK Inhibitor$119.00Catalog No. M60080A highly potent, selective, and orally bioavailable MEK inhibitor in clinical trials.Methoxy-X04, Fluorescent Amyloid (A ) ProbeMethoxy-X04, Fluorescent Amyloid (A ) ProbeMethoxy-X04, Fluorescent Amyloid (A ) Probe$79.00Catalog No. M60135A fluorescent amyloid (A ) probe for the detection and quantification of plaques, tangles and cerebrovascular amyloid with good specificity.MHY1485, mTOR ActivatorMHY1485, mTOR ActivatorMHY1485, mTOR Activator$49.00Catalog No. M60189A novel potent, selective and cell-permeable mTOR activator.MI-2, Menin-MLL Inhibitor MI-2, Menin-MLL InhibitorMI-2, Menin-MLL Inhibitor$119.00Catalog No. M66046A highly potent and selective small molecule directly binding to MALT1 and irreversibly suppressing its protease function.MK-1775 (AZD1775), WEE1 Inhibitor MK-1775 (AZD1775), WEE1 InhibitorMK-1775 (AZD1775), WEE1 Inhibitor$129.00Catalog No. M60299A highly potent, selective and orally bioavailable Wee1 kinase inhibitor.ML141, Cdc42 GTPase InhibitorML141, Cdc42 GTPase InhibitorML141, Cdc42 GTPase Inhibitor$109.00Catalog No. M60134A potent, selective and reversible non-competitive inhibitor of Cdc42 GTPase.ML228, HIF Pathway ActivatorML228, HIF Pathway ActivatorML228, HIF Pathway Activator$129.00Catalog No. M60130A potent and selective hypoxia inducible factor (HIF) pathway activator.ML239, Breast Cancer Stem Cell InhibitorML239, Breast Cancer Stem Cell InhibitorML239, Breast Cancer Stem Cell Inhibitor$129.00Catalog No. M60282A potent and selective breast cancer stem cell inhibitor.ML323, USP1-UAF1 Inhibitor ML323, USP1-UAF1 InhibitorML323, USP1-UAF1 Inhibitor$139.00Catalog No. M60188A potent, selective and reversible inhibitor of the USP1-UAF1 deubiquitinase complex.ML324, JMJD2 Histone Demethylase Inhibitor ML324, JMJD2 Histone Demethylase InhibitorML324, JMJD2 Histone Demethylase Inhibitor$139.00Catalog No. M60183A potent, selective and cell permeable inhibitor of Jumonji domain-containing protein 2 (JMJD2) histone demethylase.MLN8237 (Alisertib), Aurora A inhibitor MLN8237 (Alisertib), Aurora A inhibitorMLN8237 (Alisertib), Aurora A inhibitor$119.00Catalog No. M60093A highly potent and selective Aurora A inhibitor with 200-fold selective towards Aurora B.MM-102, WDR5-MLL1 AntagonistMM-102, WDR5-MLL1 AntagonistMM-102, WDR5-MLL1 Antagonist$129.00Catalog No. M60166A highly potent and selective inhibitor of the MLL1/WDR5 interaction.MRT68921, Autophagy Kinase ULK1/2 Inhibitor MRT68921, Autophagy Kinase ULK1/2 InhibitorMRT68921, Autophagy Kinase ULK1/2 Inhibitor$109.00Catalog No. M60311A potent, selective and dual autophagy kinase ULK1/2 inhibitor.MS023, PRMT Inhibitor MS023, PRMT InhibitorMS023, PRMT Inhibitor$109.00Catalog No. M60314A potent, selective and cell permeable type I PRMT inhibitor.MS049, PRMT4 and PRMT6 Inhibitor MS049, PRMT4 and PRMT6 InhibitorMS049, PRMT4 and PRMT6 Inhibitor$89.00Catalog No. M60310A potent, selective and cell permeable PRMT4 and PRMT6 inhibitor.MS436, BRD4 Inhibitor MS436, BRD4 InhibitorMS436, BRD4 Inhibitor$109.00Catalog No. M60232A potent and selective BET bromodomain inhibitor for BRD4 (1) and BRD4 (2).MSAB, -catenin InhibitorMSAB, -catenin InhibitorMSAB, -catenin Inhibitor$129.00Catalog No. M60316A potent and selective Wnt/ -catenin inhibitor identified using cell-based chemical screening.N106, SERCA2a SUMOylation ActivatorN106, SERCA2a SUMOylation ActivatorN106, SERCA2a SUMOylation Activator$129.00Catalog No. M60271A potent SERCA2a SUMOylation activator, which increases SUMOylation of SERCA2a.N3-tri-EG-OSuN3-tri-EG-OSuN3-tri-EG-OSuInquiryCatalog No. L60004Click chemistry linkerNAB2, Rsp5/Nedd4 pathway activator, rescuing -synuclein toxicityNAB2, Rsp5/Nedd4 pathway activator, rescuing -synuclein toxicityNAB2, Rsp5/Nedd4 pathway activator, rescuing -synuclein toxicity$129.00Catalog No. M60153A novel and highly potent small molecule Rsp5/Nedd4 pathway activator that was shown to strongly and selectively protect diverse cell types from -synuclein toxicity.Napabucasin (BBI608), STAT3 InhibitorNapabucasin (BBI608), STAT3 InhibitorNapabucasin (BBI608), STAT3 Inhibitor$89.00Catalog No. M60303A potent and selective STAT3 inhibitor.Neural-LSBNeural-LSBNeural-LSB$79.00Catalog No. S10001Combination of LDN193189 (BMP inhibitor) and SB431542 (TGF inhibitor) can rapidly and efficiently induce neural differentiation of human ESC and iPSC in 5 days.Neuronal-LSB3iNeuronal-LSB3iNeuronal-LSB3i$329.00Catalog No. S10002Combination of LSB and three other inhibitors/3i (i.e., CHIR99021/GSK3 inhibitor, SU5402/FGF-VEGF-PDGF inhibitor, DAPT/Notch inhibitor) can induce very rapid and efficient neuronal differentiation of human ESC and iPSC into nociceptors.NI-57, BRPF Bromodomain InhibitorNI-57, BRPF Bromodomain InhibitorNI-57, BRPF Bromodomain Inhibitor$109.00Catalog No. M60279A potent and selective inhibitor of the bromodomain of the BRPFs.NLG919 (RG6078), IDO InhibitorNLG919 (RG6078), IDO InhibitorNLG919 (RG6078), IDO Inhibitor$129.00Catalog No. M60258A potent, selective and orally bioavailable IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor.NMS-859, ATPase VCP/p97 InhibitorNMS-859, ATPase VCP/p97 InhibitorNMS-859, ATPase VCP/p97 Inhibitor$139.00Catalog No. M60148A potent and specific small molecule covalent inhibitor of the ATPase VCP/p97.NMS-873, ATPase VCP/p97 Inhibitor NMS-873, ATPase VCP/p97 InhibitorNMS-873, ATPase VCP/p97 Inhibitor$139.00Catalog No. M60165A potent and specific small molecule allosteric inhibitor of the ATPase VCP/p97.NMS-873/BulkNMS-873/BulkNMS-873/Bulk$0.00Catalog No. M60165-bNSC319726, Mutant p53 Activator NSC319726, Mutant p53 ActivatorNSC319726, Mutant p53 Activator$89.00Catalog No. M66047A potent and selective activator of the most common p53R175 mutant, restoring the mutant p53 to its WT structure and function.NSC636819, KDM4A/KDM4B InhibitorNSC636819, KDM4A/KDM4B InhibitorNSC636819, KDM4A/KDM4B Inhibitor$109.00Catalog No. M60290A cell permeable and selective novel active-site KDM4A/KDM4B inhibitor.NSC697923, Ub-conjugating Enzyme (E2) InhibitorNSC697923, Ub-conjugating Enzyme (E2) InhibitorNSC697923, Ub-conjugating Enzyme (E2) Inhibitor$69.00Catalog No. M60202A cell permeable, potent and selective inhibitor of the Ub-conjugating enzyme (E2) complex Ubc13-Uev1A.NU9056--- KAT5 (Tip60) Histone Acetyltransferase InhibitorNU9056--- KAT5 (Tip60) Histone Acetyltransferase InhibitorNU9056--- KAT5 (Tip60) Histone Acetyltransferase Inhibitor$69.00Catalog No. M60147A potent and selective KAT5 (Tip60) histone acetyltransferase inhibitor.NVP-BGT226, PI3K/mTOR Dual InhibitorNVP-BGT226, PI3K/mTOR Dual InhibitorNVP-BGT226, PI3K/mTOR Dual Inhibitor$89.00Catalog No. M66050A PI3K/mTOR dual inhibitor in clinical trials for advanced solid tumors.NVP-BKM120, PI3K Inhibitor BKM120NVP-BKM120, PI3K Inhibitor BKM120NVP-BKM120, PI3K Inhibitor BKM120$89.00Catalog No. M66051A selective PI3K Inhibitor in clinical trials for advanced solid tumors.NVP-TNKS656, Wnt / Tankyrase Inhibitor NVP-TNKS656, Wnt / Tankyrase InhibitorNVP-TNKS656, Wnt / Tankyrase Inhibitor$109.00Catalog No. M60328A highly potent, selective and oral bioavailable tankyrase inhibitor for TNKS2.NVS-SM1, SMN2 Splicing ModulatorNVS-SM1, SMN2 Splicing ModulatorNVS-SM1, SMN2 Splicing Modulator$129.00Catalog No. M60277A highly potent, selective and orally active small molecule SMN2 splicing modulator enhancing SMN exon 7 inclusion.NVS-SM1BulkNVS-SM1BulkNVS-SM1Bulk$0.00Catalog No. M60277-bOAC1, Oct4 ActivatorOAC1, Oct4 ActivatorOAC1, Oct4 Activator$109.00Catalog No. M60086A potent Oct4 activator significantly enhancing iPSC reprogramming efficiency and accelerating the reprogramming process.OF-1, BRPF Bromodomain Inhibitor OF-1, BRPF Bromodomain InhibitorOF-1, BRPF Bromodomain Inhibitor$129.00Catalog No. M60222A potent and selective BRPF (BRomodomain and PHD Finger containing) inhibitor.OG-L002, LSD1 InhibitorOG-L002, LSD1 InhibitorOG-L002, LSD1 Inhibitor$89.00Catalog No. M60161A highly potent and specific inhibitor of Lysine Specific Demethylase-1 (LSD1).OICR9429, WDR5 AntagonistOICR9429, WDR5 AntagonistOICR9429, WDR5 Antagonist$129.00Catalog No. M60255 A potent and selective WD repeat-containing protein 5 (WDR5) antagonist.ONX-0914, Immunoproteasome InhibitorONX-0914, Immunoproteasome InhibitorONX-0914, Immunoproteasome Inhibitor$139.00Catalog No. M60112A potent and selective immunoproteasome inhibitor.Optovin, TRPA1 ActivatorOptovin, TRPA1 ActivatorOptovin, TRPA1 Activator$129.00Catalog No. M60103A potent and selective small molecule activator of human| TRPA1.ORY-1001 (RG-6016), LSD1 InhibitorORY-1001 (RG-6016), LSD1 InhibitorORY-1001 (RG-6016), LSD1 Inhibitor$129.00Catalog No. M60295A highly potent and selective inhibitor of Lysine Specific Demethylase 1 (LSD1) in phase I/II.OSI-027, mTOR InhibitorOSI-027, mTOR InhibitorOSI-027, mTOR Inhibitor$109.00Catalog No. M60113OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2OTX015, BET Inhibitor OTX015, BET InhibitorOTX015, BET Inhibitor$89.00Catalog No. M60193OTX015 is a novel, highly potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3 and BRD4 with IC50 of 10-19 nM.P22077, USP7 inhibitorP22077, USP7 inhibitorP22077, USP7 inhibitor$99.00Catalog No. M60019A potent and selective USP7 inhibitor.P5091, Ubiquitin-specific Protease 7 (USP7) InhibitorP5091, Ubiquitin-specific Protease 7 (USP7) InhibitorP5091, Ubiquitin-specific Protease 7 (USP7) Inhibitor$79.00Catalog No. M60205P5091 (P005091) is a novel potent and selective inhibitor of ubiquitin-specific protease 7 (USP7)P7C3, Neuroprotective Small MoleculeP7C3, Neuroprotective Small MoleculeP7C3, Neuroprotective Small Molecule$119.00Catalog No. M60017A neuroprotective small molecule with favorable in vivo PK; protects newborn neurons from apoptosis.PBIT, JARID1 Histone Demethylases InhibitorPBIT, JARID1 Histone Demethylases InhibitorPBIT, JARID1 Histone Demethylases Inhibitor$129.00Catalog No. M60170PBIT is a potent, specific, reversible and cell-permeable inhibitor of Jumonji AT-Rich Interactive Domain 1 (JARID1) histone demethylases.PCI-34051, HDAC8 InhibitorPCI-34051, HDAC8 InhibitorPCI-34051, HDAC8 Inhibitor$79.00Catalog No. M60178PCI-34051 is a potent and selective inhibitor of histone deacetylase 8 (HDAC8).PD-1/PD-L1 Inhibitor C1PD-1/PD-L1 Inhibitor C1PD-1/PD-L1 Inhibitor C1$109.00Catalog No. M60312A potent and selective small molecule inhibitor of the PD-1/PD-L1 protein/protein interactions.PD0325901, MEK InhibitorPD0325901, MEK InhibitorPD0325901, MEK Inhibitor$69.00Catalog No. M60018A potent and selective MEK inhibitor.PF-04979064, PI3K/mTOR Dual InhibitorPF-04979064, PI3K/mTOR Dual InhibitorPF-04979064, PI3K/mTOR Dual Inhibitor$149.00Catalog No. M60114PF-04979064 is a highly potent and orally bioavailable PI3K/mTOR dual inhibitor developed through structure-based drug design.PF-CBP1，CBP/p300 Bromodomain Inhibitor PF-CBP1，CBP/p300 Bromodomain InhibitorPF-CBP1，CBP/p300 Bromodomain Inhibitor$129.00Catalog No. M60313A potent and selective CBP/p300 bromodomain inhibitor.PFI-1, BET InhibitorPFI-1, BET InhibitorPFI-1, BET Inhibitor$129.00Catalog No. M60120PFI-1 is a novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2 and BRD4.PFI-2, SETD7 Histone Lysine Methyltransferase Inhibitor PFI-2, SETD7 Histone Lysine Methyltransferase InhibitorPFI-2, SETD7 Histone Lysine Methyltransferase Inhibitor$139.00Catalog No. M60182PFI-2 is a novel potent and selective SETD7 histone lysine methyltransferase inhibitor.PFI-3, SMARCA Bromodomains InhibitorPFI-3, SMARCA Bromodomains InhibitorPFI-3, SMARCA Bromodomains Inhibitor$139.00Catalog No. M60175PFI-3 is a novel potent, selective and cell permeable inhibitor of SMARCA4 and PB1(5) bromodomains.PFI-4, BRPF1 Bromodomain InhibitorPFI-4, BRPF1 Bromodomain InhibitorPFI-4, BRPF1 Bromodomain Inhibitor$129.00Catalog No. M60264A potent, selective and cell permeable BRPF1 bromodomain inhibitor.Phospho-HDAC4 (Ser632) AntibodyPhospho-HDAC4 (Ser632) AntibodyPhospho-HDAC4 (Ser632) Antibody$0.00Catalog No. A90009-5aPhospho-HDAC4 (Ser632) AntibodyPhospho-HDAC4 (Ser632) AntibodyPhospho-HDAC4 (Ser632) Antibody$0.00Catalog No. A90009Phospho-HDAC4 (Ser632) Antibody. Histone deacetylase 4 (HDAC4) is a histone deacetylase that represses transcription when tethered to a promoter.PluriSIn#1, Pluripotent Cell-specific Inhibitor PluriSIn#1, Pluripotent Cell-specific InhibitorPluriSIn#1, Pluripotent Cell-specific Inhibitor$109.00Catalog No. M60085A potent small molecule to selectively eliminate human pluripotent stem cells/hPSCs while sparing a large array of tissue-specific stem/progenitor and differentiated cells.pNSC-CSBpNSC-CSBpNSC-CSB$69.00Catalog No. S10003Combination of CHIR99021 (GSK3 inhibitor) and SB431542 (TGF inhibitor) with human LIF can efficiently induce and long-term homogenously expand primitive neural stem cells from human ESC and iPSC.PP242, mTORC1/mTORC2 inhibitorPP242, mTORC1/mTORC2 inhibitorPP242, mTORC1/mTORC2 inhibitor$69.00Catalog No. M60094A highly potent, selective and ATP-competitive mTORC1/mTORC2 inhibitor.PR-619, Deubiquitinylating Enzyme (DUB) Inhibitor PR-619, Deubiquitinylating Enzyme (DUB) InhibitorPR-619, Deubiquitinylating Enzyme (DUB) Inhibitor$59.00Catalog No. M60199PR-619 is a cell-permeable, non-selective, reversible broad-range inhibitor of the deubiquitinylating enzymes (DUBs).PRMT1-2e, Protein Arginine Methyltransferase 1 (PRMT1) Inhibitor PRMT1-2e, Protein Arginine Methyltransferase 1 (PRMT1) InhibitorPRMT1-2e, Protein Arginine Methyltransferase 1 (PRMT1) Inhibitor$69.00Catalog No. M60181PRMT1-2e is a potent, specific and cell permeable inhibitor of protein arginine methyltransferase 1 (PRMT1).PRT4165, E3 Ubiquitin-ligase Bmi1/Ring1A InhibitorPRT4165, E3 Ubiquitin-ligase Bmi1/Ring1A InhibitorPRT4165, E3 Ubiquitin-ligase Bmi1/Ring1A Inhibitor$39.00Catalog No. M60245A potent and selective E3 Ubiquitin-ligase Bmi1/Ring1A Inhibitor.PS48---PDK1 ActivatorPS48---PDK1 ActivatorPS48---PDK1 Activator$79.00Catalog No. M60026An allosteric small molecule activator of PDK1.PTC-209, BMI-1 InhibitorPTC-209, BMI-1 InhibitorPTC-209, BMI-1 Inhibitor$129.00Catalog No. M60159PTC-209 is a novel potent and selective BMI-1 inhibitor, targeting the BMI-1 self-renewal machinery.PTC-209BulkPTC-209BulkPTC-209Bulk$0.00Catalog No. M60159-bPurmorphamine, Hedgehog Agonist Purmorphamine, Hedgehog AgonistPurmorphamine, Hedgehog Agonist$99.00Catalog No. M66055A selective hedgehog pathway agonist (Smo agonist).PX-478, Hypoxia-inducible Factor-1 (HIF-1 ) Inhibitor PX-478, Hypoxia-inducible Factor-1 (HIF-1 ) InhibitorPX-478, Hypoxia-inducible Factor-1 (HIF-1 ) Inhibitor$129.00Catalog No. M60227A highly potent and selective Hypoxia-inducible Factor-1 (HIF-1 ) inhibitor.Py-ds-But-OSuPy-ds-But-OSuPy-ds-But-OSuInquiryCatalog No. L60003Disulfide prodrug linkerPYR-41---Ubiquitin-activating Enzyme E1 Inhibitor PYR-41---Ubiquitin-activating Enzyme E1 InhibitorPYR-41---Ubiquitin-activating Enzyme E1 Inhibitor$59.00Catalog No. M60201PYR-41 is a specific and cell permeable inhibitor of ubiquitin-activating enzyme E1Pyrintegrin---Cell Survival EnhancerPyrintegrin---Cell Survival EnhancerPyrintegrin---Cell Survival Enhancer$109.00Catalog No. M60028A potent small molecule promoting hESC survivalPYZD-4409, Ubiquitin-activating Enzyme (E1) Inhibitor PYZD-4409, Ubiquitin-activating Enzyme (E1) InhibitorPYZD-4409, Ubiquitin-activating Enzyme (E1) Inhibitor$139.00Catalog No. M60213A novel potent, selective and cell permeable inhibitor of ubiquitin-activating enzyme (E1).RA190, Ubiquitin Receptor RPN13/ADRM1 InhibitorRA190, Ubiquitin Receptor RPN13/ADRM1 InhibitorRA190, Ubiquitin Receptor RPN13/ADRM1 Inhibitor$139.00Catalog No. M60163A novel potent and selective inhibitor of proteasome Ubiquitin receptor RPN13/ADRM1.RA190bulkRA190bulkRA190bulk$0.00Catalog No. M60163-bRapamycin, mTOR inhibitor Rapamycin, mTOR inhibitorRapamycin, mTOR inhibitor$89.00Catalog No. M60029A potent and selective mTOR inhibitor, directly binding to the mTOR Complex 1 (mTORC1).Recombinant Human Activin ARecombinant Human Activin ARecombinant Human Activin A$3900.00Catalog No. G2001601-1MGn/aRecombinant Human Basic Fibroblast Growth FactorRecombinant Human Basic Fibroblast Growth FactorRecombinant Human Basic Fibroblast Growth Factor$995.00Catalog No. G2001602-1MGn/aRecombinant Human Epidermal Growth FactorRecombinant Human Epidermal Growth FactorRecombinant Human Epidermal Growth Factor$140.00Catalog No. G2001603-1MGn/aRecombinant Human Insulin-like Growth Factor-1Recombinant Human Insulin-like Growth Factor-1Recombinant Human Insulin-like Growth Factor-1$235.00Catalog No. G2001604-1MGn/aRecombinant Human Plaet-Derived Growth Factor-BBRecombinant Human Plaet-Derived Growth Factor-BBRecombinant Human Plaet-Derived Growth Factor-BB$3200.00Catalog No. G2001605-1MGn/aRecombinant Human| Transforming Growth Factor,Beta 1Recombinant Human| Transforming Growth Factor,Beta 1Recombinant Human| Transforming Growth Factor,Beta 1$5050.00Catalog No. G2001606-1MGn/aRecombinant Mouse Basic Fibroblast Growth FactorRecombinant Mouse Basic Fibroblast Growth FactorRecombinant Mouse Basic Fibroblast Growth Factor$880.00Catalog No. G2001652-1MGn/aRecombinant Mouse Epidermal Growth FactorRecombinant Mouse Epidermal Growth FactorRecombinant Mouse Epidermal Growth Factor$220.00Catalog No. G2001653-1MGn/aRecombinant Mouse Leukemia Inhibitory FactorRecombinant Mouse Leukemia Inhibitory FactorRecombinant Mouse Leukemia Inhibitory Factor$2640.00Catalog No. G2001651-1MGn/aRemodelin, Acetyl-transferase NAT10 InhibitorRemodelin, Acetyl-transferase NAT10 InhibitorRemodelin, Acetyl-transferase NAT10 Inhibitor$139.00Catalog No. M60187Remodelin is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.RepSox---TGF- Type I Receptor ALK5 Inhibitor RepSox---TGF- Type I Receptor ALK5 InhibitorRepSox---TGF- Type I Receptor ALK5 Inhibitor$79.00Catalog No. M60151RepSox (E-616452 or SJN 2511) is a highly potent, selective inhibitor of the TGF- type I receptor ALK5.RG108---DNA Methyltransferase InhibitorRG108---DNA Methyltransferase InhibitorRG108---DNA Methyltransferase Inhibitor$65.00Catalog No. M60176RG108 is a potent, selective and cell permeable inhibitor of DNA methyltransferase.RG2833 (RGFP109), Brain-penetrant HDAC InhibitorRG2833 (RGFP109), Brain-penetrant HDAC InhibitorRG2833 (RGFP109), Brain-penetrant HDAC Inhibitor$69.00Catalog No. M60225A potent and selective brain-penetrant HDAC inhibitor HDAC1 and HDAC3.RGFP966, HDAC3 Inhibitor RGFP966, HDAC3 InhibitorRGFP966, HDAC3 Inhibitor$89.00Catalog No. M60156RGFP966 is a potent and selective HDAC3 inhibitor.RN-1, LSD1 Inhibitor RN-1, LSD1 InhibitorRN-1, LSD1 Inhibitor$109.00Catalog No. M60169RN-1 is a potent, specific and brain-penetrant Lysine Specific Demethylase-1 (LSD1) inhibitor.RO4929097, -Secretase InhibitorRO4929097, -Secretase InhibitorRO4929097, -Secretase Inhibitor$109.00Catalog No. M60007A potent and selective -secretase inhibitor; inhibits Notch signaling in stem cells and tumor cells.RS-1, CRISPR Editing Enhancer RS-1, CRISPR Editing EnhancerRS-1, CRISPR Editing Enhancer$89.00Catalog No. M60300Previously characterized as a RAD51-Stimulatory compound and now found to be an HDR enhancer to enhance CRISPR/Cas9- and TALEN-mediated knock-in efficiencyRU-SKI 43, Hhat InhibitorRU-SKI 43, Hhat InhibitorRU-SKI 43, Hhat Inhibitor$139.00Catalog No. M60100The first potent and specific small molecule inhibitor of Hedgehog acyltransferase (Hhat).RVX-208, BET Bromodomain InhibitorRVX-208, BET Bromodomain InhibitorRVX-208, BET Bromodomain Inhibitor$59.00Catalog No. M60177RVX-208 is a potent and selective BET bromodomain inhibitor for the second bromodomain (BD2), ~170-fold selectivity over BD1.Ryuvidine, Lysine Methyltransferase SETD8 InhibitorRyuvidine, Lysine Methyltransferase SETD8 InhibitorRyuvidine, Lysine Methyltransferase SETD8 Inhibitor$129.00Catalog No. M60252A potent, selective and cell permeable lysine methyltransferase SETD8 inhibitor.SAG, Hedgehog AgonistSAG, Hedgehog AgonistSAG, Hedgehog Agonist$129.00Catalog No. M60081A potent, selective, and cell-permeable small-molecule agonist of the Hedgehog pathway.SB431542, TGF-beta InhibitorSB431542, TGF-beta InhibitorSB431542, TGF-beta Inhibitor$300.00Catalog No. M60015A potent and selective TGF- pathway inhibitor (selective for ALK4, ALK5 and ALK7).SBI-0206965, Autophagy Kinase ULK1 InhibitorSBI-0206965, Autophagy Kinase ULK1 InhibitorSBI-0206965, Autophagy Kinase ULK1 Inhibitor$129.00Catalog No. M60268A potent, selective and cell permeable autophagy kinase ULK1 inhibitor.SCH51344, MTH1 Inhibitor SCH51344, MTH1 InhibitorSCH51344, MTH1 Inhibitor$139.00Catalog No. M60212A novel potent, selective and cell permeable MTH1 inhibitor.SCR7, NHEJ inhibitorSCR7, NHEJ inhibitorSCR7, NHEJ inhibitor$129.00Catalog No. M60082A potent and selective inhibitor of non-homologous end joining (NHEJ).SD70, Histone Demethylase JMJD2 Inhibitor SD70, Histone Demethylase JMJD2 InhibitorSD70, Histone Demethylase JMJD2 Inhibitor$139.00Catalog No. M60194A potent, selective and cell-permeable inhibitor of histone demethylase JMJD2 (KDM4C).Sephin1, PPP1R1 Protein Phosphatase InhibitorSephin1, PPP1R1 Protein Phosphatase InhibitorSephin1, PPP1R1 Protein Phosphatase Inhibitor$129.00Catalog No. M60280A potent, selective and bioavailable inhibitor of the regulatory subunit PPP1R1 of protein phosphatase 1.SGC-CBP30, p300/CBP Bromodomain Inhibitor SGC-CBP30, p300/CBP Bromodomain InhibitorSGC-CBP30, p300/CBP Bromodomain Inhibitor$139.00Catalog No. M60138SGC-CBP30 is a highly potent and selective p300/CBP bromodomain inhibitorSGC0946, DOT1L inhibitor SGC0946, DOT1L inhibitorSGC0946, DOT1L inhibitor$139.00Catalog No. M60101A highly potent and selective inhibitor of DOT1L methyltransferase.SGC707, Allosteric PRMT3 InhibitorSGC707, Allosteric PRMT3 InhibitorSGC707, Allosteric PRMT3 Inhibitor$129.00Catalog No. M60243A potent, selective and cell permeable allosteric protein arginine methyltransferase 3 (PRMT3) inhibitor.SGI-1027, DNMT InhibitorSGI-1027, DNMT InhibitorSGI-1027, DNMT Inhibitor$89.00Catalog No. M60155A potent and selective inhibitor of DNA methyltransferase (DNMT).SHP099, SHP2 Phosphatase InhibitorSHP099, SHP2 Phosphatase InhibitorSHP099, SHP2 Phosphatase Inhibitor$139.00Catalog No. M60319A highly potent, selective and orally bioavailable small-molecule SHP2 inhibitor.SirReal2, Sirt2 InhibitorSirReal2, Sirt2 InhibitorSirReal2, Sirt2 Inhibitor$119.00Catalog No. M60289A potent and selective Sirt2 inhibitor.SIRT1 Polyclonal AntibodySIRT1 Polyclonal AntibodySIRT1 Polyclonal Antibody$0.00Catalog No. A90007SIRT1 Polyclonal Antibody: SIRT1 is a nuclear protein that regulates epigenetic gene silencing and suppresses recombination of rDNASKP2-C25, Skp2 InhibitorSKP2-C25, Skp2 InhibitorSKP2-C25, Skp2 Inhibitor$139.00Catalog No. M60136A potent, selective and cell permeable Skp2 inhibitor, selectively inhibits Skp2 E3 ligase activity, but not activity of other SCF complexes.SKPin C1, Skp2 Inhibitor SKPin C1, Skp2 InhibitorSKPin C1, Skp2 Inhibitor$109.00Catalog No. M60137A potent and selective inhibitor of Skp2-mediated p27 degradation.SMER3, SCF family E3 Ubiquitin Ligase Inhibitor SMER3, SCF family E3 Ubiquitin Ligase InhibitorSMER3, SCF family E3 Ubiquitin Ligase Inhibitor$129.00Catalog No. M60250A potent and selective a yeast SCF family E3 ubiquitin ligase inhibitor, also a small-molecule enhancers of rapamycin.Spautin-1, Autophagy InhibitorSpautin-1, Autophagy InhibitorSpautin-1, Autophagy Inhibitor$69.00Catalog No. M60003A potent autophagy inhibitor, selectively promotes the degradation of Vps34 complexes.SR10067, REV-ERB AgonistSR10067, REV-ERB AgonistSR10067, REV-ERB Agonist$129.00Catalog No. M60240A potent and specific synthetic REV-ERB agonist.SR1664,PPAR- ModulatorSR1664,PPAR- ModulatorSR1664,PPAR- Modulator$109.00Catalog No. M66048An unique PPAR modulator that has potent anti-diabetic activity through blocking the Cdk5-mediated phosphorylation of PPAR , but compley lacks classical transcriptional agonism that accounts for other PPAR agonists side effects.SR9009, REV-ERB AgonistSR9009, REV-ERB AgonistSR9009, REV-ERB Agonist$109.00Catalog No. M60236A potent and specific synthetic REV-ERB agonist.SR9011SR9011SR9011$1250.00Catalog No. M66049-bSR9011, REV-ERB AgonistSR9011, REV-ERB AgonistSR9011, REV-ERB Agonist$109.00Catalog No. M66049A potent synthetic REV-ERB agonist with in vivo activity; can regulate circadian behavior and metabolism.SR9011-cSR9011-cSR9011-c$1250.00Catalog No. SR9011-cSR9243, LXR Inverse AgonistSR9243, LXR Inverse AgonistSR9243, LXR Inverse Agonist$129.00Catalog No. M60270A highly potent and selective small molecule LXR inverse agonist that induces LXR-corepressor interaction.StemRegenin1 (SR1)---HSC Expansion MoleculeStemRegenin1 (SR1)---HSC Expansion MoleculeStemRegenin1 (SR1)---HSC Expansion Molecule$99.00Catalog No. M60001A potent and selective aryl hydrocarbon receptor antagonist; can promote robust expansion of human CD34+ hematopoietic stem and progenitor cells.SU5402---FGFR inhibitor SU5402---FGFR inhibitorSU5402---FGFR inhibitor$89.00Catalog No. M60025A potent and selective inhibitor of FGFR, VEGFR, and PDGFR.SW033291, 15-PGDH InhibitorSW033291, 15-PGDH InhibitorSW033291, 15-PGDH Inhibitor$99.00Catalog No. M60298A highly potent and selective inhibitor of 15-PGDH to increase prostaglandin PGE2 levels in bone marrow and other tissues.TAK-875 (Fasiglifam), GPR40 AgonistTAK-875 (Fasiglifam), GPR40 AgonistTAK-875 (Fasiglifam), GPR40 Agonist$139.00Catalog No. M60220A potent, selective and orally bioavailable partial GPR40 agonist.TAME, Ubiquitin Ligase APC/C InhibitorTAME, Ubiquitin Ligase APC/C InhibitorTAME, Ubiquitin Ligase APC/C Inhibitor$29.00Catalog No. M60246A competitive inhibitor of the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C).Tasquinimod, Allosteric HDAC4 InhibitorTasquinimod, Allosteric HDAC4 InhibitorTasquinimod, Allosteric HDAC4 Inhibitor$129.00Catalog No. M60235A potent and selective allosteric HDAC4 inhibitor.TCID, Ubiquitin C-terminal Hydrolase-L3 (UCH-L3) Inhibitor TCID, Ubiquitin C-terminal Hydrolase-L3 (UCH-L3) InhibitorTCID, Ubiquitin C-terminal Hydrolase-L3 (UCH-L3) Inhibitor$99.00Catalog No. M60197A novel potent and selective inhibitor of ubiquitin C-terminal hydrolase-L3 (UCH-L3)TEPP-46 (ML265), Pyruvate Kinase M2 (PKM2) ActivatorTEPP-46 (ML265), Pyruvate Kinase M2 (PKM2) ActivatorTEPP-46 (ML265), Pyruvate Kinase M2 (PKM2) Activator$129.00Catalog No. M60304A potent and selective Pyruvate kinase M2 (PKM2) activator.TG101348 (SAR302503), JAK2 and BRD4 Dual Inhibitor TG101348 (SAR302503), JAK2 and BRD4 Dual InhibitorTG101348 (SAR302503), JAK2 and BRD4 Dual Inhibitor$109.00Catalog No. M60172TG101348 is a potent, specific and orally bioavailable inhibitor of JAK2 and BRD4 in clinical trials.TH-302, Hypoxia-activated Pro-drugTH-302, Hypoxia-activated Pro-drugTH-302, Hypoxia-activated Pro-drug$179.00Catalog No. M60089A highly potent and selective hypoxia-activated pro-drug targeting hypoxic regions of solid tumors.TH588, MTH1 InhibitorTH588, MTH1 InhibitorTH588, MTH1 Inhibitor$139.00Catalog No. M60211A novel potent, selective and cell permeable MTH1 inhibitor.Thiazovivin, Rock Inhibitor Thiazovivin, Rock InhibitorThiazovivin, Rock Inhibitor$79.00Catalog No. M60009A more potent and selective Rock inhibitor; can enhance hESC and hiPSC survival from single cell dissociation.THZ1, Covalent CDK7 InhibitorTHZ1, Covalent CDK7 InhibitorTHZ1, Covalent CDK7 Inhibitor$159.00Catalog No. M60214A novel potent, selective and cell permeable irreversible CDK7 inhibitor.TMP269, Class IIa HDAC InhibitorTMP269, Class IIa HDAC InhibitorTMP269, Class IIa HDAC Inhibitor$129.00Catalog No. M60119A highly potent, selective and cell-permeable class IIa HDAC inhibitor.TMPA---AMPK ActivatorTMPA---AMPK ActivatorTMPA---AMPK Activator$119.00Catalog No. M60072TMPA is a novel small molecule that binds to orphan Nuclear Receptor Nur77 and activates AMPK.TRIM24-C34, BRPF1B/TRIM24 Dual InhibitorTRIM24-C34, BRPF1B/TRIM24 Dual InhibitorTRIM24-C34, BRPF1B/TRIM24 Dual Inhibitor$99.00Catalog No. M60265A potent, selective and cell permeable BRPF1B and TRIM24 dual inhibitor.TRIM24-C34bulkTRIM24-C34bulkTRIM24-C34bulk$169.00$199.00Catalog No. M60265-bTRIM24-C34bulkTRIM24-C34bulkTRIM24-C34bulk$0.00Catalog No. M60265-bTZ9, Rad6 Ubiquitin Inhibitor TZ9, Rad6 Ubiquitin InhibitorTZ9, Rad6 Ubiquitin Inhibitor$109.00Catalog No. M60286A selective and cell permeable inhibitor of human E2 ubiquitin-conjugating enzyme Rad6B.UF010, HDAC InhibitorUF010, HDAC InhibitorUF010, HDAC Inhibitor$89.00Catalog No. M60278UF010 is a potent and selective class I HADC inhibitor.UM171, Human HSC Self-renewal AgonistUM171, Human HSC Self-renewal AgonistUM171, Human HSC Self-renewal Agonist$159.00Catalog No. M60223A potent small molecules that stimulates the expansion ex vivo of human cord blood cells capable of reconstituting human hematopoiesis for at least 6 months in immunocompromised mice.UNC0379, Lysine Methyltransferase SETD8 Inhibitor UNC0379, Lysine Methyltransferase SETD8 InhibitorUNC0379, Lysine Methyltransferase SETD8 Inhibitor$129.00Catalog No. M60207A novel selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8UNC0638, G9a HMTase Inhibitor UNC0638, G9a HMTase InhibitorUNC0638, G9a HMTase Inhibitor$89.00Catalog No. M66056A potent, selective and cell permeable inhibitor of G9a (EHMT2) and GLP (EHMT1) histone methyltransferases.UNC0642, G9a/GLP HMTase Inhibitor UNC0642, G9a/GLP HMTase InhibitorUNC0642, G9a/GLP HMTase Inhibitor$129.00Catalog No. M60185A novel highly potent, selective and cell permeable inhibitor of the homologous protein lysine methyltransferases, G9a and GLP, with improved PK properties.UNC0646, G9a/GLP HMTase Inhibitor UNC0646, G9a/GLP HMTase InhibitorUNC0646, G9a/GLP HMTase Inhibitor$89.00Catalog No. M60184A novel potent, selective and cell permeable homologous protein lysine methyltransferases G9a and GLP inhibitor.UNC1215, L3MBTL3 Domain InhibitorUNC1215, L3MBTL3 Domain InhibitorUNC1215, L3MBTL3 Domain Inhibitor$119.00Catalog No. M60084A highly potent and selective small molecule inhibitor for the methyl-lysine (Kme) reading function of L3MBTL3.UNC2170, Methyl-lysine Binding Protein 53BP1 InhibitorUNC2170, Methyl-lysine Binding Protein 53BP1 InhibitorUNC2170, Methyl-lysine Binding Protein 53BP1 Inhibitor$99.00Catalog No. M60260A selective and cell permeable methyl-lysine binding protein 53BP1 antagonist.UNC2327, Allosteric PRMT3 Inhibitor UNC2327, Allosteric PRMT3 InhibitorUNC2327, Allosteric PRMT3 Inhibitor$129.00Catalog No. M60253A potent and selective allosteric protein arginine methyltransferase 3 (PRMT3) inhibitor.UNC669, L3MBTL1 Domain Inhibitor UNC669, L3MBTL1 Domain InhibitorUNC669, L3MBTL1 Domain Inhibitor$89.00Catalog No. M60083A potent and selective small molecule inhibitor for the methyl-lysine (Kme) reading function of L3MBTL1Verteporfin (Visudyne), YAP InhibitorVerteporfin (Visudyne), YAP InhibitorVerteporfin (Visudyne), YAP Inhibitor$59.00Catalog No. M60247A potent and selective YAP inhibitor to disrupt YAP-TEAD interactions and enhance trypsin cleavage of YAP.VLX600, Mitochondrial OXPHOS InhibitorVLX600, Mitochondrial OXPHOS InhibitorVLX600, Mitochondrial OXPHOS Inhibitor$69.00Catalog No. M60261A potent and selective mitochondrial OXPHOS inhibitor.VR23, Proteasome InhibitorVR23, Proteasome InhibitorVR23, Proteasome Inhibitor$99.00Catalog No. M60307A potent and selective proteasome inhibitor with IC50 of 1 nM, 50-100 nM, and 3 M for trypsin-like proteasomes, chymotrypsin-like proteasomes,WAY-316606, Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor WAY-316606, Secreted Frizzled-related Protein-1 (sFRP-1) InhibitorWAY-316606, Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor$139.00Catalog No. M60215A novel potent and selective inhibitor of secreted frizzled-related protein-1 (sFRP-1) to increase Wnt signaling.WDR5-0103, WDR5 InhibitorWDR5-0103, WDR5 InhibitorWDR5-0103, WDR5 Inhibitor$89.00Catalog No. M60233A potent and selective WD repeat-containing protein 5 (WDR5) antagonist.WDR5-C47, WDR5-MLL (SET1) Antagonist WDR5-C47, WDR5-MLL (SET1) AntagonistWDR5-C47, WDR5-MLL (SET1) Antagonist$129.00Catalog No. M60118A highly potent and selective antagonist of WDR5-MLL interaction.Wnt-C59, Wnt Antagonist Wnt-C59, Wnt AntagonistWnt-C59, Wnt Antagonist$89.00Catalog No. M60005A potent, selective and oral active Wnt signaling pathway antagonist.WP1130 (Degrasyn), Deubiquitinylating Enzyme (DUB) Inhibitor WP1130 (Degrasyn), Deubiquitinylating Enzyme (DUB) InhibitorWP1130 (Degrasyn), Deubiquitinylating Enzyme (DUB) Inhibitor$69.00Catalog No. M60206A cell-permeable, potent and selective inhibitor of the deubiquitinylating enzymes (DUBs).WS3, Cell Proliferation Inducer WS3, Cell Proliferation InducerWS3, Cell Proliferation Inducer$139.00Catalog No. M60095A highly potent and selective small molecule that promotes pancreatic cell and RPE cells expansion.WS6, Cell Proliferation Inducer WS6, Cell Proliferation InducerWS6, Cell Proliferation Inducer$139.00Catalog No. M60097A highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets and shows excellent in vivo efficacy.WWL113, Ces3 and Ces1f Inhibitor WWL113, Ces3 and Ces1f InhibitorWWL113, Ces3 and Ces1f Inhibitor$139.00Catalog No. M60162A novel potent and selective inhibitor of Ces3 and Ces1fXAV939---Wnt Antagonist XAV939---Wnt AntagonistXAV939---Wnt Antagonist$89.00Catalog No. M60010A potent and selective Wnt pathway antagonist; functions to stabilize axin by inhibiting tankyrase 1 and tankyrase 2.XL888---HSP90 InhibitorXL888---HSP90 InhibitorXL888---HSP90 Inhibitor$149.00Catalog No. M60164A highly potent, ATP-competitive and orally bioavailable Hsp90 inhibitor.Y-27632---Rock Inhibitor Y-27632---Rock InhibitorY-27632---Rock Inhibitor$69.00Catalog No. M60011The most widely used Rock kinase inhibitor.Y-320---IL-17 ImmunomodulatorY-320---IL-17 ImmunomodulatorY-320---IL-17 Immunomodulator$89.00Catalog No. M60200An orally active potent immunomodulator, inhibits IL-15-induced IL-17 production by CD4 T cells.ZCL278---Cdc42 GTPase InhibitorZCL278---Cdc42 GTPase InhibitorZCL278---Cdc42 GTPase Inhibitor$119.00Catalog No. M60133A potent and selective inhibitor of Cdc42 GTPase.ZLN005---PGC-1 Transcriptional ActivatorZLN005---PGC-1 Transcriptional ActivatorZLN005---PGC-1 Transcriptional Activator$69.00Catalog No. M60142 A potent and selective small molecule PGC-1 transcriptional activator.