Cat. No.: 218 211Amount: 100 µgPrice:415.00€Add to CartCat.No.218211100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100µlH2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use. ApplicationsWB:1 : 500 up to 1 : 1000(see remarks) galleryIP:not tested yetICC:not tested yetIHC:1 : 500 up to 1 : 1000(see remarks) galleryIHC-P/FFPE:1 : 1000 up to 1 : 2000galleryELISA:yes (see remarks) CloneNT244SubtypeIgG2b (κ light chain)ImmunogenSynthetic peptide corresponding to AA 1 to 16 from human Abeta (UniProt Id: P05067)EpitopEpitop: AA 4 to 8 from human Abeta (UniProt Id: P05067)ReactivityReacts with: human (P05067), mouse (P12023).Other species not tested yet.SpecificitySpecific for Abeta 38, 40, 42, 43.RemarksWB:Boil membrane after blotting for 3min.IHC:Antigen retrieval with formic acid is required.ELISA:Suitable as detector antibodies with cat.no.218203, 218403 and 218703 as capture antibodies.Data sheet218_211.pdfReferences for Abeta 38/40/42/43 - 218211 Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer"s Disease.PorcellottiS, FanelliF, FracassiA, SepeS, CecconiF, BernardiC, CiminiA, CerùMP, MorenoSOxidative medicine and cellular longevity (2015) 2015: 967203. 218211 IHC Aβ38 in the brains of patients with sporadic and familial Alzheimer"s disease and transgenic mouse models.ReinertJ, MartensH, HuettenrauchM, KolbowT, LannfeltL, IngelssonM, PaetauA, Verkkoniemi-AholaA, BayerTA, WirthsOJournal of Alzheimer"s disease : JAD (2014) 394: 871-81. 218211 IHC; tested species: human Oligomeric pyroglutamate amyloid-β is present in microglia and a subfraction of vessels in patients with Alzheimer"s disease: implications for immunotherapy.WirthsO, HillmannA, PradierL, HärtigW, BayerTAJournal of Alzheimer"s disease : JAD (2013) 354: 741-9. 218211 IHC; tested species: human Antibody 9D5 recognizes oligomeric pyroglutamate amyloid-β in a fraction of amyloid-β deposits in Alzheimer"s disease without cross-reactivity with other protein aggregates.VenkataramaniV, WirthsO, BudkaH, HärtigW, KovacsGG, BayerTAJournal of Alzheimer"s disease : JAD (2012) 292: 361-71. 218211 IHC; tested species: human