Cat. No.: 218 231Amount: 100 µgPrice:415.00€Add to CartCat.No.218231100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100µlH2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use. ApplicationsWB:not tested yetIP:not tested yetICC:not tested yetIHC:1 : 100 up to 1 : 500galleryIHC-P/FFPE:1 : 100 up to 1 : 200galleryClone80C2SubtypeIgG2a (κ light chain)ImmunogenSynthetic peptide corresponding to AA 1 to 5 from human Abeta (UniProt Id: P05067)EpitopEpitop: AA 1 to 5 from human Abeta (UniProt Id: P05067)ReactivityReacts with: human (P05067), mouse (P12023).Other species not tested yet.SpecificitySpecific for Abeta 38, 40, 42, 43. No cross-reactivity to N-terminally truncated Abeta species.Data sheet218_231.pdfReferences for Abeta 1-5 - 218231 N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer"s disease.ZamparS, KlafkiHW, SritharenK, BayerTA, WiltfangJ, RostagnoA, GhisoJ, AMilesL, WirthsONeuropathology and applied neurobiology (2020) : . 218231 WB, IHC-P; tested species: human N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer"s disease.ZamparS, KlafkiHW, SritharenK, BayerTA, WiltfangJ, RostagnoA, GhisoJ, AMilesL, WirthsONeuropathology and applied neurobiology (2020) : . 218231 WB, IHC-P; tested species: human The presubiculum is preserved from neurodegenerative changes in Alzheimer"s disease.MurrayCE, Gami-PatelP, GkanatsiouE, BrinkmalmG, PorteliusE, WirthsO, HeywoodW, BlennowK, GhisoJ, HoltonJL, MillsK, et al.Acta neuropathologica communications (2018) 61: 62. 218231 IHC-P; tested species: human The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer"s disease.WalterS, JumpertzT, HüttenrauchM, OgorekI, GerberH, StorckSE, ZamparS, DimitrovM, LehmannS, LepkaK, BerndtC, et al.Acta neuropathologica (2018) : . 218231 IHC-P; tested species: mouse