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DETAILSDescription:This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples. Type:AssayMax ELISA KitsSamples:SerumPlasmaCell CultureUrineSalivaMilkCatalog Number:EC3001-1Species:NoneFormat:Competitive ELISASize:96 Well PlateRange:0.391 - 100 ng/mlResearch Area:Adrenal, Cardiac DisorderSynonyms:corticosterone, cort, corticoNote:For Research Use Only, Not To Be Used For Diagnostic PurposesProduct References:*Ohkawara T et al. (2005) Transgenic over-expression of macrophage migration inhibitory factor renders mice markedly more susceptible to experimental colitis. Clin Exp Immunol.140(2):241-248*Sugiyama1 F et al. (2006) Soybean isoflavones preserve bone mass in hindlimb-unloaded mice. J Bone Miner Metab. 24(6):439-446*Nakano1 S et al. 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(2008) Overexpression of Thioredoxin-1 Reduces Oxidative Stress in the Placenta of Transgenic Mice and Promotes Fetal Growth via Glucose Metabolism.Endocrinology 149(8):3980-3988*Satvat E (2009) Neural and Behavioural Effects of the Ginkgo biloba Leaf Extract Egb 761. Theses and Dissertations (Comprehensive). Paper 1070*Beaulieu M et al. (2010) Ecophysiological response of Adelie penguins facing an experimental increase in breeding constraints. J. Experimental Biology 213:33-39 *Beaulieu M et al. (2010) When sea-ice clock is ahead of Adelie penguins? clock.Functional Ecology 24:93-102*Chai W (2010) Steroidogenesis vs. steroid uptake in the heart: do corticosteroids mediate effects via cardiac mineralocorticoid receptors? J. Hypertension 28:1044-1053 *Gamliel-Lazarovich A et al. (2010) Paraoxonase 1 deficiency in mice is associated with reduced steroid biosynthesis: Effects on HDL binding, cholesteryl ester accumulation and scavenger receptor type BI expression. 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Learning Memory 17:552-560 *Schulz K and Korz V (2010) Hippocampal testosterone relates to reference memory performance and synaptic plasticity in male rats. Front Behav Neurosci. 4:187 *Spee M et al. (2010) Should I stay or should I go? Hormonal control of nest abandonment in a long-lived bird, the Adelie penguin. Horm. Behav. 58(5):762-8 * Toriya M et al. (2010) Long-term Infusion of Brain-Derived Neurotrophic Factor Reduces Food Intake and Body Weight via a Corticotrophin-Releasing Hormone Pathway in the Paraventricular Nucleus of the Hypothalamus. J. Neuroendocrinology 22:987-995*Yoshida N et al. (2010) Stressor-responsive central nesfatin-1 activates corticotropin-releasing hormone, noradrenaline and serotonin neurons and evokes hypothalamic-pituitary-adrenal axis. Aging 2(11):775-784* Allende ML et al. (2011) Sphingosine-1-phosphate Lyase Deficiency Produces a Pro-inflammatory Response While Impairing Neutrophil Trafficking. J Biol Chem. 286(9):7348-58 *Avital A et al. (2011) Environmental Enrichment Preceding Early Adulthood Methylphenidate Treatment Leads to Long Term Increase of Corticosterone and Testosterone in the Rat. PLoS One. 6(7):e22059 *Cui H et al. (2011) Metabolic Cycles Are Linked to the Cardiovascular Diurnal Rhythm in Rats with Essential Hypertension. PLoS One. 6(2):e17339*Liang G et al. (2011) Ethanol-induced inhibition of fetal hypothalamic-pituitary-adrenal axis due to prenatal overexposure to maternal glucocorticoid in mice. Exp Toxicol Pathol. 63(7-8):607-611*Momken I et al. (2011) Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat. FASEB J. 25(10):3646-3660* Murakami T et al. (2011) Rapid induction of REDD1 expression by endurance exercise in rat skeletal muscle. Biochem Biophys Res Commun. 405(4):615-619.*Nakamura Y et al. (2011) Circadian clock gene Period2 regulated a time-of-day-dependent variation in curaneous anaphylactic reaction. J Allergy Clin Immunol. 127(4):1038-45.e1-3*Oh YT et al. (2011) Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue. Am J Physiol Endocrinol Metab 300(6): E1012-E1021*Schroeder M et al. (2011) Enriched Environment Moderates Obesity in Genetically Hyperphagic OLETF Rats in a Sex-dependent Manner. ILAR e-Journal. 52:e39-e45 *Spee M et al. (2011) Exogenous corticosterone and nest abandonment: A study in a long-lived bird, the Adelie penguin. Horm Behav. 60(4):362-70. Epub 2011 Jul 13 *Spee M et al. (2011) Exogenous corticosterone mimics a late fasting stage in captive Adelie penguins (Pygoscelis adeliae). Am J Physiol Regul Integr Comp Physiol 300: R1241-R1249*Tang JI (2011) Prenatal Glucocorticoid Programming of 11-beta Hydoxysteroid Dehydrogenase Type 2 and Erythropoietin in the Kieney. The University of Edinburgy.*Tang JI et al. (2011) Prenatal Glucocorticoid Overexposure Causes Permanent Increases in Renal Erythropoietin Expression and Red Blood Cell Mass in the Rat Offspring. Endocrinology. 152(7):2716-2721*Tanaka M et al. (2011) Role of Central Leptin Signaling in the Starvation-Induced Alteration of B-Cell Development. J Neurosci. 31(23):8373-8380*Terada Y et al. (2011) Dietary Vitamin E Deficiency Increases Anxiety-Like Behavior in Juvenile and Adult Rats. Biosci Biotechnol Biochem. 2011;75(10):1894-9. Epub 2011 Oct 7* Wang Z et al (2011) Preventive Action of Panax ginseng Roots in Hypercortisolism-induced Impairment of Hippocampal Neurons in Male C57BL/6N Mice. Phytother Res. 25(8):1242-1245.*Williams CL et al. (2011) Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspring. BMC Biol. 9:49* Young TO at al. (2011) Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue. Am J Physiol Endocrinol Metab. 300(6): E1012?E1021*Edelstein S et al. (2012) Salvia sclarea seed oil for use in the treatment of cardiovascular diseases or anxiety disorders. Patent Application number: WO2012156970 A1*Fukada M et al. (2012 ) Loss of Deacetylation Activity of Hdac6 Affects Emotional Behavior in Mice. PLoS One. 7(2):e30924 *Jeanneteau FD et al. (2012) BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus. Proc Natl Acad Sci U S A. 109(4):1305-1310* Ikeda Y et al. (2012) Heat shock protein expression inducer. Patent application: WO2012043808 A1, PCT / JP2011 / 072592 * Kondo S et al. (2015) Antidepressant-like effects of rosmarinic acid through mitogen-activated protein kinase phosphatase-1 and brain-derived neurotrophic factor modulation. Journal of Functional Foods. 14:758-766* Kogure M et al. (2012) Moxibustion at Mingmen Reduces Inflammation and Decreases IL-6 in a Collagen-Induced Arthritis Mouse Model. J Acupunct Meridian Stud. 5(1):29-33*LeGates TA et al. (2012) Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. 491(7425):594-598*Mahmoud UT et al. (2012) The Effect of Separate-Sex Rearing of Slaughter Quail on Serum Corticosterone Level. Journal of Advanced Veterinary Research 2:206-207 *Moussaieff A et al. (2012) Incensole acetate reduces depressive-like behavior and modulates hippocampal BDNF and CRF expression of submissive animals. J Psychopharmacol 26(12):1584-1593*Sherman H et al. (2012) Timed high-fat diet resets circadian metabolism and prevents obesity. FASEB J. 26(8):3493-3502* Sujino M et al. (2012) Differential Entrainment of Peripheral Clocks in the Rat by Glucocorticoid and Feeding. Endocrinology 153(5):2277-2286* Yamada H et al. (2012) Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine gamma-lyase, an animal model of cystathioninuria. Free Radic Biol Med. 52(9):1716-1726*Yanai S (2012) Remarkable Changes in Behavior and Physiology of Laboratory Mice after the Massive 2011 Tohoku Earthquake in Japan. PLoS One. 7(9):e44475 *Yoshioka M et al. (2012) Effects of Parabolic Flight on Serotonin-Related Gene Expression in the Mouse Brain. Gravitational and Space Biology 26 (2):22-29*Chapnik N et al. (2013) A superactive leptin antagonist alters metabolism and locomotion in high leptin mice. J Endocrinol. 217(3):283-90 *Hayasaka D et al. (2013) TNF-alpha Acts as an Immunoregulator in the Mouse Brain by Reducing the Incidence of Severe Disease Following Japanese Encephalitis Virus Infection. PLoS ONE. 8(8):e71643*Sakai H et al. (2013) Effects of radiofrequency Radiation at 40 kHz on stress-induced immune response in mice. J.Rakuno Gakuen Univ. 37(2):189-194*Liston C et al. (2013) Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance. Nature Neuroscience 16:698-705 *McGuire JL et al.(2013) Traits of fear resistance and susceptibility in an advanced intercross line. Eur J Neurosci. 38(9):3314-24. doi: 10.1111/ejn.12337. Epub 2013 Aug 22*Miyazaki K et al. (2013) Continuous exposure to a novel stressor based on water aversion induces abnormal circadian locomotor rhythms and sleep-wake cycles in mice. PLoS One. 8(1):e55452. Epub 2013 Jan 30*Oishi K and Ohkura N (2013) Chronic circadian clock disruption induces expression of the cardiovascular risk factor plasminogen activator inhibitor-1 in mice. Blood Coagul Fibrinolysis. 24(1):106-8*Othman MB et al. (2013) Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in Tunisia.Evidence-Based Complementary and Alternative Medicine.Volume 2013 (2013), Article ID 737401, 9 pages* Oue H et al. (2013) Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice. Behav Brain Res. 252:318-325* Shinohara H et al. (2013) Medium-chain fatty acid-containing dietary oil alleviates the depression-like behaviour in mice exposed to stress due to chronic forced swimming. Journal of Funtional Foods. 5(2):601-606*Spinelli S et al. (2013) Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression. Front Behav Neurosci. 2013 Dec 31;7:215* Tabassum H et al. (2013) The effect of acute swim stress and training in the water maze on hippocampal synaptic activity as well as plasticity in the dentate gyrus of freely moving rats: Revisiting swim?induced LTP reinforcement. Hippocampus. 23(12):1291-8*Thierry AM et al. (2013) Decreased prolactin levels reduce parental commitment, egg temperatures, and breeding success of incubating male Adelie penguins. Hormones and Behavior 64 (4):737-747 *Torres OV et al. (2013) Behavioral, Biochemical, and Molecular Indices of Stress are Enhanced in Female Versus Male Rats Experiencing Nicotine Withdrawal. Front Psychiatry. 2013 May 20;4:38* Wilson CL et al. (2013) Chemotherapy drug thioTEPA exacerbates stress-induced anhedonia and corticosteroid responses but not impairment of hippocampal cell proliferation in adult mice. Behav Brain Res. 236(1):180-185*Abe K et al. (2014) Withdrawal of repeated morphine enhances histamine-induced scratching responses in mice. Drug Chem Toxicol. 4:1-7*Bentley L et al. (2014) An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess.Endocrinology. 155(3):908-22.Epub 2013 Dec 3. *Cottin M et al. (2014) Corticosterone administration leads to a transient alteration of foraging behaviour and complexity in a diving seabird. Marine Ecology Progress Series 496:249-262 * Cottin M et al. (2014) Decreasing prolactin levels leads to a lower diving effort but does not affect breeding success in Ad?lie penguins. Hormones and Behavior. 65(2):134-141.*Hiramoto K et al. (2014) Relationship between alteration of the peptide hormone levels and depression during the gestational period. Res.J.Endocrinol. Metab. 2:1. * Jung SM et ahcl. (2014) Cytokine-Mediated Bone Destruction in Rheumatoid Arthritis. J Immunol Res. 2014:263625*Kuhn E et al. (2014) Paradoxical resistance to high-fat diet-induced obesity and altered macrophage polarization in mineralocorticoid receptor-overexpressing mice. Am J Physiol Endocrinol Metab. 306(1):E75-90. doi: 10.1152/ajpendo.00323.2013. Epub 2013 Nov 12.* Mizuki D et al. (2014) Antidepressant-like effect of Butea superba in mice exposed to chronic mild stress and its possible mechanism of action. J Ethnopharmacol. 156:16-25* Nakamura Y et al. (2014) Circadian regulation of allergic reactions by the mast cell clock in mice. J. Allergy Clin. Immunol. 133 (2):568-575* Nahata M et al. (2014) Administration of exogenous acylated ghrelin or rikkunshito, an endogenous ghrelin enhancer, improves the decrease in postprandial gastric motility in an acute restraint stress mouse model. Neurogastroenterol Motil. 26:821-831*Takemoto H et al. (2014) Inhalation administration of valerena-4,7(11)-diene from Nardostachys chinensis roots ameliorates restraint stress-induced changes in murine behavior and stress-related factors. Biol Pharm Bull. 37(6):1050-5* Tamura Y et al. (2014) Postexercise whole body heat stress additively enhances endurance training-induced mitochondrial adaptations in mouse skeletal muscle.Am J Physiol Regul Integr Comp Physiol. 307(7):R931-43*Guillou A et al. (2015) Assessment of Lactotroph Axis Functionality in Mice: Longitudinal Monitoring of PRL Secretion by Ultrasensitive-ELISA. Endocrinology. 156(5):1924-1930*Hori A et al. (2015) Kososan, but not milnacipran, elicits antidepressant-like effects in a novel psychological stress-induced mouse model of depression. Traditional & Kampo Medicine 2(1):1-7*Iwasaki S et al. (2015) Brief fear preexposure facilitates subsequent fear conditioning. Neurosci Res. 95:66-73* Nagahama K et al. (2015) Effect of kumquat (Fortunella crassifolia) pericarp on natural killer cell activity in vitro and in vivo. Biosci Biotechnol Biochem. 79(8):1327-36.* Nakao R et al. (2015) Atypical expression of circadian clock genes in denervated mouse skeletal muscle. Chronobiol Int. 2015 May;32(4):486-96. doi:10.3109/07420528.2014.1003350. Epub 2015 Mar 23* Oishi K et al. (2015) Disrupted light?dark cycle abolishes circadian expression of peripheral clock genes without inducing behavioral arrhythmicity in mice. Biochem Biophys Res Commun. 458(2):256-261* Shimizu S (2015) Yokukansan normalizes glucocorticoid receptor protein expression in oligodendrocytes of the corpus callosum by regulating microRNA-124a expression after stress exposure. Brain Res Bull. 114:49-55* Zhang H et al. (2015) Chronic corticosterone exposure reduces hippocampal astrocyte structural plasticity and induces hippocampal atrophy in mice. Neurosci Lett. 592:76-81* Yasumoto Y et al. (2015) Free Access to a Running-Wheel Advances the Phase of Behavioral and Physiological Circadian Rhythms and Peripheral Molecular Clocks in Mice. PLoS One. 2015; 10(1): e0116476* Antunes MS et al. (2015) Neuropeptide Y administration reverses tricyclic antidepressant treatment-resistant depression induced by ACTH in mice. Horm Behav. 73:56-63* Bath KG et al. (2016) Early life stress accelerates behavioral and neural maturation of the hippocampus in male mice. Horm Behav. 82:64-71 * Bertile F (2016) The Safety Limits Of An Extended Fast: Lessons from a Non-Model Organism. Sci Rep. 2016 Dec 19;6:39008* Lesburgueres et al.(2016) Active place avoidance is no more stressful than unreinforced exploration of a familiar environment. Hippocampus. 26(12):1481-1485.* Mukuta K et al. (2016) Administration of Tomato Juice or Aqueous Components of Tomato Reduces Fatigue Induced by Acute Treadmill Exercise. Food and Nutritiion Sciences. 7(7):524-532.* Nakamura Y et al. (2016) Effects of inducing exercise on growing mice by means of three-dimensional structure in rearing environment. Exp Anim. 65(4): 403-411* Ono M. et al. (2016) Does the routine handling affect the phenotype of disease model mice? Japanese Journal of Veterinary Research 64(4): 265-271* Uwaya A et al. (2016) Acute immobilization stress following contextual fear conditioning reduces fear memory: timing is essential. Behav Brain Funct. 12(1):8 * Uwaya A. et al. (2016) Acute immobilization stress following contextual fear conditioning reduces fear memory: timing is essential. Behav Brain Funct. 12(1):8* Yasumoto Y et al. (2016) Short-term feeding at the wrong time is sufficient to desynchronize peripheral clocks and induce obesity with hyperphagia, physical inactivity and metabolic disorders in mice. Metabolism. 65(5):714-727* Youcef G et al. (2016) Preventive and chronic mineralocorticoid receptor antagonism is highly beneficial in obese SHHF rats. Br J Pharmacol. 173(11):1805-1819.* Beaulieu M et al. (2017) Socially-induced variation in physiological mediators of parental care in a colonial bird. Horm Behav. 93:39-46* Chen L et al. (2017) Preventive effects of ginseng total saponins on chronic corticosterone?induced impairment in astrocyte structural plasticity and hippocampal atrophy. Phytother Res. 31(9):1341-1348* Homma T et al. (2017) Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a). 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(2017) Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice. Sci Rep. 7(1):8802* Oishi K et al. (2018) Chronic sleep disorder induced by psychophysiological stress induces glucose intolerance without adipose inflammation in mice. Biochem Biophys Res Commun. 495(4):2616-2621* Yoshida S et al. (2018) Corticotropin-Releasing Factor Receptor 1 in the Anterior Cingulate Cortex Mediates Maternal Absence-Induced Attenuation of Transport Response in Mouse Pups. Front. Cell. Neurosci. 12: 1-14.* Chu H et al. (2019) Sleep deprivation modifies noise-induced cochlear injury related to the stress hormone and autophagy in female mice. Front Neurosci. 13:1297* Gao C et al. (2019) Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression. Med Sci Monit. 25: 389?394* Nakao R et al. (2019) Ketogenic diet induces skeletal muscle atrophy via reducing muscle protein synthesis and possibly activating proteolysis in mice. Sci Rep. 9(1):19652.* Rettig TA et al.(2019) Effects of skeletal unloading on the antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice. PLOS ONE images/Assaypro/article January 17, 2019* Terao R et al. (2019) Immunostimulatory effect of kumquat (Fortunella crassifolia) and its constituents, beta-cryptoxanthin and R-limonene. Food Funct. 10(1):38-48. * Tung TH et al. (2019) Fish Oil, but Not Olive Oil, Ameliorates Depressive-Like Behavior and Gut Microbiota Dysbiosis in Rats under Chronic Mild Stress. Biomolecules 9(10):10.3390/biom9100516* Wilcox AG (2019) Circadian characterisation of the transcription factor Zfhx3 utilising a conditional mutagenesis approach. University of Oxford. Ph.D. Thesis (Corticosterone kit)* Campos P et al. (2020) Diving into the brain: deep-brain imaging techniques in conscious animals. J Endocrinol. pii: JOE-20-0028.R1. doi: 10.1530/JOE-20-0028
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