Echelon Biosciences成立于1997年10月3日，总部坐落于在美国犹他州。从1997到2004，EBI主要用于政府的补助金以及产品的销售收入来资助其研究工作。2005年初，EBI的依特钠Zentaris购买 （NAS：AEZS）的MEP抗感染，PI3激酶小分子程序，目录业务，与科学专业。2007年末，前沿科学公司（FSI）在洛根，犹他州购买了EBI， 专业从事卟啉和硼化学。自公司成立以来以来，EBI保留了开发研究试剂脂质新的检测方法。不断开拓创新，从而推动药物研究的新发型。

Echelon Biosciences是美国著名免疫学产品供应商，专业提供各种抗体、分析检测试剂盒、抑制剂等产品，尤其擅长以细胞信号、脂类代谢和标记物研究为主的相关产品。为研究治疗诸如癌症、糖尿病、炎症、感染和心脑血管疾病专家提供全面有效工具。

Echelon Biosciences产品线

Lipid Kinases Phosphatases

脂质激酶和磷酸

Lipid-Protein Interaction Tools

脂蛋白质相互作用工具

Lipid-Specific Assay Kits

脂质特定检测试剂盒

Lipid-Specific Antibodies Binding Proteins

脂质特定抗体和结合蛋白

Hyaluronic Acid Collagen IV Assay Kits

透明质酸和IV型胶原检测试剂盒

Synthetic Inositol phosphates, Lipids, Phospholipids

合成的磷酸肌醇，脂和磷脂

PI3-Kinase PI3-激酶

Echelon Biosciences可提供PI3-Kinase 实验解决全套方案，从分析服务到实验用抗体、酶和抑制剂等，全面满足科研需求。

专业系列

产品编号

特色产品

Kits

试剂盒

K-1000

PI3-K ELISA Kit

 K-1000S

PI3-K ELISA: Pico Assay

K-1100

PI3-K Fluorescence Polarization Kit

K-1300

PI3-K AlphaScreen®

 K-2700S

TRueFRET PI3-K Activity Assay

K-3000

Class III PI3-K ELISA Kit

Antibodies

抗体

Z-R015

Anti-huVps34 (Class III PI3-Kinase) Antibody for IP

Z-R016

Anti-huVps34 (Class III PI3-Kinase) Antibody for WB

Inhibitors

抑制剂

B-0021

Resveratrol (Class IA PI3-K Inhibitor)

B-0222

Wortmannin (PI3-Kinase Inhibitor)

B-0294

PI3-Kinase Inhibitor (LY294002)

B-0301

PI3-Kinase Gamma Inhibitor 1 (AS605240)

B-0302

PI3-Kinase Gamma Inhibitor 2 (AS604850

B-0303

PI3-Kinase Alpha Inhibitor 1 (PI-103)

B-0304

PI3-Kinase Alpha Inhibitor 2

Enzymes

酶

 P27-18H

PI3-K (p-110 alpha/p85 alpha) Active Enzyme

 P28-10H

PI3-K (p-110 beta/p85 alpha) Active Enzyme

Lysolipids 血溶性脂类

Lysolipid Pathway                                            Synthetic Lysophosphatidic Acid (LPA)◆ Inhibitors 抑制剂系列                                  ◆ Labeled 标记物系列◆ Ligands 配体系列                                        ◆ Ligands 配体系列◆ Analogs 类似物系列                                    ◆ Saturated 底物系列                                                                         ◆ Unsaturated 不饱和系列 

专业系列

产品标号

特色产品

Kits试剂盒

 K-2800B

Lysophosphatidic Acid Competitive ELISA Kit

K-4100

Autotaxin Activity Assay

K-4200

Autotaxin Inhibitor Screening Kit

Enzymes酶

E-4000

Autotaxin Enzyme

Substrate底物

L-2000

FS-3 LysoPLD/Autotaxin Substrate

Inhibitors抑制剂

L-7416

LysoPLD/Autotaxin Inhibitor

Sphingolipids 鞘脂类

Synthetic Sphingolipids

◆ Sphingosine 鞘氨醇                           ◆ Ceramide 神经酰胺

◆ Sphingosine 1 Phosphate (S1P ) 鞘氨醇磷酸酯     ◆ Sphingomyelin 鞘磷脂

◆ FTY720P 

专业系列

产品编号

特色产品

Kits

试剂盒

K-1900

Sphingosine 1 Phosphate ELISA Kit (S1P)

K-3500

Sphingosine Kinase 1 Activity Assay

K-1800

Sphingomyelinase Assay Kit

K-3200

Acid Sphingomyelinase Assay Kit

Enzymes

酶

E-K068

Sphingosine Kinase 1, active

E-K069

Sphingosine Kinase 2, active

Inhibitors

抑制剂

B-0024

Sphingosine Kinase Inhibitor

产品编号

特色产品

S-400B

Sphingomyelin Biotin

 P-B0SM

Sphingomyelin Beads

S-6100

Sphingosine Beads

S-6110

Sphingosine 1 Phosphate Beads

 P-B00Ss

Sphingo Bead Sample Pack

 G-SM01

Sphingomyelin Grip (Equinatoxin)

Autotaxin(ATX) 自分泌运动因子

Echelon Biosciences是世界上唯完整全面提供Autotaxin(ATX) 和Autotaxin(ATX) 相关试剂的供应商。

产品编号

特色产品

K-4100

Autotaxin Activity Assay Kit

K-4200

Autotaxin Inhibitor Screening Kit

 K-2800B

Lysophosphatidic Acid Competitive ELISA Kit

L-2000

FS-3 (LysoPLD / Autotaxin Substrate)

L-7416

BrP-LPA Autotaxin Inhibitor

E-4000

Autotaxin Enzyme

Echelon Biosciences目的在于进一步发展的脂质的细胞信号转导的关键代谢酶的科学，它提供了对癌症，心血管疾病疾病，糖尿病，炎症，感染的潜在的药物和诊断发展的新的和可行的目标。

Echelon Biosciences为生命科学社区提供的产品包括：

抗体            分析检测试剂盒

抑制剂           细胞信号产品

脂类代谢          标记物

              Z-R015    Anti-huVps34 （Class III PI3-Kinase） Antibody for IP抗体            Z-R016    Anti-huVps34 （Class III PI3-Kinase） Antibody for WB

               K-1000    PI3-K ELISA Kit试剂盒       K-1000S    PI3-K ELISA: Pico Assay                  K-1100    PI3-K Fluorescence Polarization Kit                  K-1300    PI3-K AlphaScreen®                  K-2700S    TRueFRET PI3-K Activity Assay                  K-3000    Class III PI3-K ELISA Kit

              P27-18H    PI3-K （p-110 alpha/p85 alpha） Active Enzyme酶               P28-10H    PI3-K （p-110 beta/p85 alpha） Active Enzyme              B-0021    Resveratrol （Class IA PI3-K Inhibitor）抑制剂        B-0222    Wortmannin （PI3-Kinase Inhibitor）                   B-0294    PI3-Kinase Inhibitor （LY294002）                   B-0301    PI3-Kinase Gamma Inhibitor 1 （AS605240）                   B-0302    PI3-Kinase Gamma Inhibitor 2 （AS604850                   B-0303    PI3-Kinase Alpha Inhibitor 1 （PI-103）                   B-0304    PI3-Kinase Alpha Inhibitor 2

Echelon Biosciences Incorporated (EBI) was incorporated under the laws of the state of Utah as Echelon Research Laboratories, Inc. on October 3, 1997. Initially, Echelon Biosciences EBI was formed from a project under the Center for Cell Signaling, a State of Utah Center of Excellence, with the aim to further the science of lipid cell signaling and critical metabolic enzymes, which provide new and viable targets for the development of potential drugs and diagnostics for cancer, diabetes, inflammation, infections, and cardiovascular disease.

From 1997 through 2004, Echelon Biosciences EBI primarily used government grants and product sales revenues to fund its research efforts. In early 2005, EBI was purchased by Aeterna Zentaris (NAS: AEZS) for its MEP anti-infectives, PI3-Kinase small molecule program, catalog business, and scientific expertise. In late 2007, Frontier Scientific Incorporated (FSI) based in Logan, Utah purchased EBI. Specializing in porphyrin and boron chemistry, FSI opened the doors for expanded research.

Since 1997, Echelon Biosciences EBI has retained its commitment to developing novel assays and reagents for lipid research and beyond. At EBI’s core is the desire to innovate, thus pushing medicinal research to new limits. We look forward to providing scientists around the world with the tools they need to cure human disease states for years to come and we welcome any suggestions about how we can better do so.

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