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Angiopoietin-like Protein 7; Cornea-derived Transcript 6 Protein

Monoclonal Antibody

Kairos 397-7

Mouse IgG1κ

Recombinant human full length ANGPTL7.

ELISA: (direct or indirect: 1:500-1:5000)Western blot: (1:500-1:5000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature).Optimal conditions should be determined individually for each application.

Human

Recognizes human ANGPTL7. Detects a band of ~45kDa by Western blot. Weakly cross-reacts with the fibrinogen-like domain (FLD) of human ANGPTL7.

Protein G-affinity purified.

1mg/ml

Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

BLUE ICE

+4°C

-20°C

After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.

Stable for at least 1 year after receipt when stored at -20°C.

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ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.