Enzolifesciences/Ghrelin (human) monoclonal antibody (45)/BPD-ABS-050-45-02/200µg
Product Specification:
| Clone: | 45 |
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| Host: | Mouse |
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| Isotype: | IgG1λ |
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| Immunogen: | Synthetic peptide corresponding to the sequence of human human Ser3-octanoyl ghrelin-28 |
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| UniProt ID: | Q9UBU3 |
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| Species reactivity: | Human |
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| Applications: | ELISA, WB |
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| Purity Detail: | Protein A affinity purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Ghrelin is an orexigenic (food intake stimulating) 27 or 28 amino-acid gut-brain peptide hormone produced by endocrine cells in the stomach, pancreatic islets and certain hypothalamic neurons. Two forms are produced by alternative mRNA splicing; Gln13 or 14 is missing from the second form. \"Active\" ghrelin is acylated (octanoylated) at Ser3; this form stimulates growth hormone secretion via GHS receptors and increases appetite. The des-acyl form does not have these effects but may have other actions. Plasma responses of total ghrelin to food may reflect those of active ghrelin. |
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