Enzolifesciences/CEACAM8 (human) monoclonal antibody (GM2H6)/ALX-805-088-C100/100µg
Product Specification:
| Alternative Name: | Carcinoembryonic antigen-related cell adhesion molecule 8, CD66b |
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| Clone: | GM2H6 |
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| Host: | Mouse |
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| Isotype: | IgG1 |
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| Immunogen: | Vector containing the cDNA of human CEACAM8. |
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| UniProt ID: | P31997 |
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| Species reactivity: | Human |
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| Crossreactivity: | Does not cross-react with human CEACAM1, 3, 4, 5, 6, 7, or PSG1. |
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| Applications: | ELISA, Flow Cytometry |
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| Recommended Dilutions/Conditions: | Competitive ELISA (1.2µg/106 cells)Flow Cytometry (1:200-1:400)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. |
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| Purity Detail: | Protein G-affinity purified. |
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| Quality Control: | Specificity routinely tested by flow cytometry on CEACAM8 transfected BOSC23 cells. |
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| Formulation: | Liquid. In PBS, pH 7.2. Contains no preservatives. |
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| Handling: | For maximum product recovery after thawing, centrifuge the vial before opening the cap. Avoid freeze/thaw cycles. |
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| Shipping: | Shipped on Blue Ice |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -20°C |
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| Scientific Background: | CEA-related cell adhesion molecule 8 (CEACAM8) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a molecular mass of of 95kD and is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. Therefore CEACAM8 could serve as a marker for granulocyte activities. Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B domains. |
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