Enzolifesciences/Clostridium tetani toxoid monoclonal antibody (6E7)/BPD-HYB-278-17-02/200µg
Product Specification:
| Clone: | 6E7 |
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| Host: | Mouse |
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| Isotype: | IgG1κ |
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| Immunogen: | Tetanus toxoid. |
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| UniProt ID: | P04958 |
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| Species reactivity: | Clostridium tetani |
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| Applications: | ELISA |
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| Application Notes: | Detects a band of ~150kDa by Western blot. |
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| Purity Detail: | Protein A/G-affinity purified. |
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| Formulation: | Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Short Term Storage: | +4°C |
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| Scientific Background: | Clostridium tetani is a Gram-positive, motile bacterium found in soil and animal feces. Toxigenic strains of C. tetani contain a plasmid encoding the potent exotoxin which causes tetanus (lockjaw). The toxin is synthesized as a single 150kDa protein chain which is cleaved (\"nicked\") into a 100kDa heavy chain (fragment B) and a 50kDa light chain (fragment A) connected by a disulfide bridge. Tetanus toxoid is produced by prolonged incubation of the toxin with formaldehyde and lysine, and is often used as a carrier for compounds of poor immunogenicity. |
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