Enzolifesciences/Glucosidase II α polyclonal antibody/ADI-VAP-PT034-C/25µl
Product Specification:
| Alternative Name: | GBA, GCB, GLUC |
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| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to a portion of human α-Glucosidase II. |
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| UniProt ID: | Q14697 |
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| Species reactivity: | Human, MouseBovine, Dog, Guinea pig, Hamster, Monkey, Rabbit, Sheep |
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| Applications: | IHC (PS), IP, WB |
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| Recommended Dilutions/Conditions: | Immunoprecipitation (1:50)Western Blot (1:500, colorimetric, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. |
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| Formulation: | Liquid. Whole rabbit serum. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Alpha-glucosidase II is a 110 kDa glycosylated ER resident protein that is involved in trimming of glucose from newly synthesized glycosylated proteins. Together with an 80 kDa beta subunit, these polypeptides remove two Alpha-1,3-linked glucose from high mannose oligosaccharides linked to asparagine residue on glycoprotein. Alpha-glucosidase II-mediated glucose trimming is necessary for the interaction of clanexin with monoglucosylated substrates such as influenza virus hemagglutinin (HA), MHC Class I, and T-cell antigen receptor (TCR). |
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