Details
H13R, a mutation in the metal-binding region of Abeta reduces its copper-mediated toxicity. The native rodent sequence containing an arginine at this position is more tolerant to metals than the human amyloid peptide.
Item Number4095736APC Number62-0-27One Letter CodeDAEFRHDSGYEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVSynonyms[Arg13] β-Amyloid (1-40)Molecular FormulaC₁₉₄H₃₀₀N₅₄O₅₈SRelative Molecular Mass4348.91CAS Registry Number[1816939-33-9] netSourceSyntheticStorage Conditions-20 ± 5 °CAreas of Interest Alzheimers Disease Links / Documents:
Brochures:
- Amyloid Peptides
- Care and Handling of Amyloid Peptides
Product citations
X.Dai et al., J. Mol. Neurosci., 41, 66 (2010) J.F.Poduslo et al., PLoS One, 5, e8813 (2010) D.P.Smith et al., J. Biol. Chem., 281, 15145 (2006)
